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MIT-001, a Mitochondria-Targeted ROS Scavenger, Ameliorates DSS-Induced Colitis and Is Associated with Reduced HMGB1 and IL-1β Expression.

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Title: MIT-001, a Mitochondria-Targeted ROS Scavenger, Ameliorates DSS-Induced Colitis and Is Associated with Reduced HMGB1 and IL-1β Expression.
Authors: Kim D; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Kim SH; Mitoimmune Therapeutics Inc., Seoul 05836, Republic of Korea., Choe JW; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Kim SY; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Hyun JJ; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Jung SW; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Jung YK; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Yim HJ; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Koo JS; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Jul 06; Vol. 27 (13). Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MIT-001, a Mitochondria-Targeted ROS Scavenger, Ameliorates DSS-Induced Colitis and Is Associated with Reduced HMGB1 and IL-1β Expression.
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  Data: <searchLink fieldCode="AU" term="%22Kim+D%22">Kim D</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Mitoimmune Therapeutics Inc., Seoul 05836, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choe+JW%22">Choe JW</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SY%22">Kim SY</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hyun+JJ%22">Hyun JJ</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+SW%22">Jung SW</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+YK%22">Jung YK</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yim+HJ%22">Yim HJ</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Koo+JS%22">Koo JS</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2026 Jul 06; Vol. 27 (13). <i>Date of Electronic Publication: </i>2026 Jul 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101092791 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1422-0067 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214220067%22">14220067 </searchLink><i>NLM ISO Abbreviation: </i>Int J Mol Sci <i>Subsets: </i>MEDLINE
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        Value: 10.3390/ijms27136051
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      – TitleFull: MIT-001, a Mitochondria-Targeted ROS Scavenger, Ameliorates DSS-Induced Colitis and Is Associated with Reduced HMGB1 and IL-1β Expression.
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            – D: 06
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              Text: 2026 Jul 06
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