Naringin and denosumab ameliorate osteoporosis and suppress the aldosterone-MR/SGK1 signaling axis by modulating the bone-kidney interorgan communication in Orchiectomized rats.

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Title: Naringin and denosumab ameliorate osteoporosis and suppress the aldosterone-MR/SGK1 signaling axis by modulating the bone-kidney interorgan communication in Orchiectomized rats.
Authors: Xiong S; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Wu G; Endoscopy Center, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, China., Zhong Y; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Xiang R; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Zhang Y; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Guo H; Spine Department, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China., Guo Z; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Lu W; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Lan Q; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Chen Y; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Li Y; Spine Department, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 Jun 30; Vol. 17, pp. 1794408. Date of Electronic Publication: 2026 Jun 30 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-2392
DOI:10.3389/fendo.2026.1794408