Naringin and denosumab ameliorate osteoporosis and suppress the aldosterone-MR/SGK1 signaling axis by modulating the bone-kidney interorgan communication in Orchiectomized rats.

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Title: Naringin and denosumab ameliorate osteoporosis and suppress the aldosterone-MR/SGK1 signaling axis by modulating the bone-kidney interorgan communication in Orchiectomized rats.
Authors: Xiong S; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Wu G; Endoscopy Center, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, China., Zhong Y; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Xiang R; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Zhang Y; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Guo H; Spine Department, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China., Guo Z; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Lu W; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Lan Q; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Chen Y; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China., Li Y; Spine Department, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 Jun 30; Vol. 17, pp. 1794408. Date of Electronic Publication: 2026 Jun 30 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Naringin and denosumab ameliorate osteoporosis and suppress the aldosterone-MR/SGK1 signaling axis by modulating the bone-kidney interorgan communication in Orchiectomized rats.
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  Data: <searchLink fieldCode="AU" term="%22Xiong+S%22">Xiong S</searchLink>; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+G%22">Wu G</searchLink>; Endoscopy Center, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, China.<br /><searchLink fieldCode="AU" term="%22Zhong+Y%22">Zhong Y</searchLink>; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xiang+R%22">Xiang R</searchLink>; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+H%22">Guo H</searchLink>; Spine Department, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+Z%22">Guo Z</searchLink>; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lu+W%22">Lu W</searchLink>; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lan+Q%22">Lan Q</searchLink>; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; The Third Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Spine Department, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101555782%22">Frontiers in endocrinology</searchLink> [Front Endocrinol (Lausanne)] 2026 Jun 30; Vol. 17, pp. 1794408. <i>Date of Electronic Publication: </i>2026 Jun 30 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101555782 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-2392 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216642392%22">16642392 </searchLink><i>NLM ISO Abbreviation: </i>Front Endocrinol (Lausanne) <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fendo.2026.1794408
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        Text: English
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      – TitleFull: Naringin and denosumab ameliorate osteoporosis and suppress the aldosterone-MR/SGK1 signaling axis by modulating the bone-kidney interorgan communication in Orchiectomized rats.
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            – D: 30
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              Text: 2026 Jun 30
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