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A conserved basic motif mediates membrane anchoring and TRAF2 recruitment across costimulatory TNFRs.

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Title: A conserved basic motif mediates membrane anchoring and TRAF2 recruitment across costimulatory TNFRs.
Authors: Zhu J; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China., Xu X; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China., Liu P; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China., Wu H; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China., Wang Y; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China., Xu B; Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Wen M; Hangzhou Weizhi Biotechnology Co., Ltd, Hangzhou, China., Chen M; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Chen Z; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China. 2305635@tongji.edu.cn., Chou JJ; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China. james_chou@mail.sioc.ac.cn.; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China. james_chou@mail.sioc.ac.cn., Zhao L; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China. lzhao@tongji.edu.cn.
Source: The EMBO journal [EMBO J] 2026 Jul 15. Date of Electronic Publication: 2026 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+P%22">Liu P</searchLink>; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xu+B%22">Xu B</searchLink>; Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wen+M%22">Wen M</searchLink>; Hangzhou Weizhi Biotechnology Co., Ltd, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China. 2305635@tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chou+JJ%22">Chou JJ</searchLink>; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China. james_chou@mail.sioc.ac.cn.; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China. james_chou@mail.sioc.ac.cn.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China. lzhao@tongji.edu.cn.
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        Value: 10.1038/s44318-026-00868-z
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              Text: 2026 Jul 15
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