Efficacy and EEG-ECG mechanisms of taVNS combined with TEAS for negative symptoms of schizophrenia: a protocol for a 2 × 2 factorial randomized controlled trial.

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Title: Efficacy and EEG-ECG mechanisms of taVNS combined with TEAS for negative symptoms of schizophrenia: a protocol for a 2 × 2 factorial randomized controlled trial.
Authors: Zhang S; The Second Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, China.; Wearable BCI and Intelligent Rehabilitation Innovation Lab, Guangzhou Institute of Technology, Xidian University, Xian, China., Gong Y; Department of Psychiatry, The First Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming, China., Zhang B; Kunming Psychiatric Hospital, Kunming, China., Cui Y; Engineering Research Center of Molecular and Neuro Imaging of the Ministry of Education, School of Life Science and Technology, Xidian University, Xian, China., Deng Y; The Second Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, China., Li Q; College of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China., Li W; The Second Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, China., Lo V; The Second Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, China., Qian J; Department of Psychiatry, Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China., Liang F; College of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China., Guo T; The Second Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, China. gtphncs@126.com., Sun J; Wearable BCI and Intelligent Rehabilitation Innovation Lab, Guangzhou Institute of Technology, Xidian University, Xian, China. sunjb@xidian.edu.cn.; Engineering Research Center of Molecular and Neuro Imaging of the Ministry of Education, School of Life Science and Technology, Xidian University, Xian, China. sunjb@xidian.edu.cn.
Source: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2026 Jul 16. Date of Electronic Publication: 2026 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9103030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-8491 (Electronic) Linking ISSN: 09401334 NLM ISO Abbreviation: Eur Arch Psychiatry Clin Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1433-8491
DOI:10.1007/s00406-026-02328-5