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The pyruvate dehydrogenase complex at the crossroads of cancer metabolism and cell death.

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Title: The pyruvate dehydrogenase complex at the crossroads of cancer metabolism and cell death.
Authors: Cai X; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China., Chen F; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China., Liang R; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China., Tang H; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China; Department of Liver Diseases, Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, China., Zhou Q; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China., Lin J; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China., Kang R; Department of Surgery, UT Southwestern Medical Center, Dallas, TX 75390, USA., Tang D; Department of Surgery, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: daolin.tang@utsouthwestern.edu., Liu J; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China. Electronic address: 2018683073@gzhmu.edu.cn.
Source: Cell chemical biology [Cell Chem Biol] 2026 Jul 16; Vol. 33 (7), pp. 966-981.
Publication Type: Journal Article; Review
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The pyruvate dehydrogenase complex at the crossroads of cancer metabolism and cell death.
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  Data: <searchLink fieldCode="AU" term="%22Cai+X%22">Cai X</searchLink>; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China.<br /><searchLink fieldCode="AU" term="%22Chen+F%22">Chen F</searchLink>; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China.<br /><searchLink fieldCode="AU" term="%22Liang+R%22">Liang R</searchLink>; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China.<br /><searchLink fieldCode="AU" term="%22Tang+H%22">Tang H</searchLink>; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China; Department of Liver Diseases, Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Q%22">Zhou Q</searchLink>; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China.<br /><searchLink fieldCode="AU" term="%22Kang+R%22">Kang R</searchLink>; Department of Surgery, UT Southwestern Medical Center, Dallas, TX 75390, USA.<br /><searchLink fieldCode="AU" term="%22Tang+D%22">Tang D</searchLink>; Department of Surgery, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: daolin.tang@utsouthwestern.edu.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; DAMP Laboratory, Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Protein Modification and Disease, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510150, China. Electronic address: 2018683073@gzhmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101676030%22">Cell chemical biology</searchLink> [Cell Chem Biol] 2026 Jul 16; Vol. 33 (7), pp. 966-981.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676030 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2451-9448 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224519448%22">24519448 </searchLink><i>NLM ISO Abbreviation: </i>Cell Chem Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.chembiol.2026.06.009
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        Text: English
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              Text: 2026 Jul 16
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