Coordinated expansion of CD163+ monocytes and immature CD177+ neutrophils marks severe neurotoxicity after CD19 CAR T cell therapy.
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| Title: | Coordinated expansion of CD163 |
|---|---|
| Authors: | Chour T; Department of Laboratory Medicine and Pathology, University of Washington.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center., Poole N; Department of Laboratory Medicine and Pathology, University of Washington.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center.; Ben Towne Center for Childhood Cancer and Blood Disorders Research, Seattle Children's Research Institute, Seattle Children's Hospital, University of Washington, Seattle, Washington., MacMillan HR; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center., Burleigh K; Ben Towne Center for Childhood Cancer and Blood Disorders Research, Seattle Children's Research Institute, Seattle Children's Hospital, University of Washington, Seattle, Washington., Glass DR; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center., Liang EC; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA., Basom R; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington., Webb-Robertson BM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington., Stratton K; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington., Gratz D; Fred Hutch Innovation Lab, Fred Hutchinson Cancer Center, Seattle, WA, USA., Long AN; Fred Hutch Innovation Lab, Fred Hutchinson Cancer Center, Seattle, WA, USA., Elz AE; Fred Hutch Innovation Lab, Fred Hutchinson Cancer Center, Seattle, WA, USA., Huang JJ; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA., Hirayama AV; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA.; Integrated Immunotherapy Research Center, Fred Hutchinson Cancer Center, Seattle, Washington.; Department of Medicine, University of Washington, Seattle, Washington., Riddell SR; Department of Medicine, University of Washington, Seattle, Washington.; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Gauthier J; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA.; Integrated Immunotherapy Research Center, Fred Hutchinson Cancer Center, Seattle, Washington.; Department of Medicine, University of Washington, Seattle, Washington., Gustafson HH; Department of Laboratory Medicine and Pathology, University of Washington.; Ben Towne Center for Childhood Cancer and Blood Disorders Research, Seattle Children's Research Institute, Seattle Children's Hospital, University of Washington, Seattle, Washington.; Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, Washington., Newell EW; Department of Laboratory Medicine and Pathology, University of Washington.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center.; Fred Hutch Innovation Lab, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Integrated Immunotherapy Research Center, Fred Hutchinson Cancer Center, Seattle, Washington., Simon S; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 Jul 09. Date of Electronic Publication: 2026 Jul 09. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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