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Synthesis, 131I-radioiodination, and biodistribution of a novel nicotinonitrile derivative with in vitro antimicrobial and DNA gyrase inhibitory activities.

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Title: Synthesis, 131I-radioiodination, and biodistribution of a novel nicotinonitrile derivative with in vitro antimicrobial and DNA gyrase inhibitory activities.
Authors: Salib BG; Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt., Essa BM; Radioactive Isotopes and Generators Department, Hot Laboratories and Waste Management Center, Egyptian Atomic Energy Authority, Cairo, 13759, Egypt., Shamsel-Din HA; Labeled Compound Department, Hot Laboratories and Waste Management Center, Egyptian Atomic Energy Authority (EAEA), Cairo, 13759, Egypt., Motaleb MA; Labeled Compound Department, Hot Laboratories and Waste Management Center, Egyptian Atomic Energy Authority (EAEA), Cairo, 13759, Egypt., El-Tawoosy M; Labeled Compound Department, Hot Laboratories and Waste Management Center, Egyptian Atomic Energy Authority (EAEA), Cairo, 13759, Egypt., Selim AA; Labeled Compound Department, Hot Laboratories and Waste Management Center, Egyptian Atomic Energy Authority (EAEA), Cairo, 13759, Egypt. adli_a_selim@yahoo.com., Rizk SA; Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt., Faraag AHI; Botany and Microbiology Department, Faculty of Science, Helwan University, Cairo, Egypt.; School of Biotechnology, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt., Ali MA; School of Biotechnology, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt., Mostafa IY; Department of Microbiology, Faculty of Dentistry and Oral Medicine, Future University, Cairo, Egypt., Mansour R; School of Biotechnology, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.; Zoology and Entomology Department, Faculty of Science, Helwan University, Helwan, 11795, Egypt., Elyan SS; School of Biotechnology, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt., Basiouny MS; School of Biotechnology, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt., Anwer KE; Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
Source: Molecular diversity [Mol Divers] 2026 Jul 17. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Synthesis, <superscript>131</superscript>I-radioiodination, and biodistribution of a novel nicotinonitrile derivative with in vitro antimicrobial and DNA gyrase inhibitory activities.
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              Text: 2026 Jul 17
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