Selective pulmonary vasorelaxant effects of an N2,N4-diaminoquinazoline PDE5 inhibitor involving endothelial signaling and ion channel modulation.

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Title: Selective pulmonary vasorelaxant effects of an N2,N4-diaminoquinazoline PDE5 inhibitor involving endothelial signaling and ion channel modulation.
Authors: Chatturong U; Department of Physiology, Faculty of Medical Science and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand., Meebangsue T; Department of Physiology, Faculty of Medical Science and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand., Guntur G; Department of Biomedical Engineering, Faculty of Engineering, King Mongkut's Institute of Technology, Ladkrabang, Bangkok, 10520, Thailand., Gleeson MP; Department of Biomedical Engineering, Faculty of Engineering, King Mongkut's Institute of Technology, Ladkrabang, Bangkok, 10520, Thailand. Electronic address: paul.gl@kmitl.ac.th., Chootip K; Department of Physiology, Faculty of Medical Science and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: krongkarnc@nu.ac.th.
Source: European journal of pharmacology [Eur J Pharmacol] 2026 Jul 17; Vol. 1030, pp. 179154. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0712
DOI:10.1016/j.ejphar.2026.179154