Disruption of CDK4/6-RARα-NF-κB axis attenuates senescence-associated inflammation and improves function during aging and following chemotherapy.
Saved in:
| Title: | Disruption of CDK4/6-RARα-NF-κB axis attenuates senescence-associated inflammation and improves function during aging and following chemotherapy. |
|---|---|
| Authors: | Wang B; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Piccolantonio A; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Altulea A; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Huang M; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Joshi T; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Pagliarin F; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Di Palma M; Department of Biomedical Sciences, University of Padova, Padova, Italy., Lin Y; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Mackedenski S; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Ustyantsev K; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Jager C; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Berezikov E; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands., Demaria M; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands. m.demaria@umcg.nl. |
| Source: | Nature aging [Nat Aging] 2026 Jul 17. Date of Electronic Publication: 2026 Jul 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42469443 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Disruption of CDK4/6-RARα-NF-κB axis attenuates senescence-associated inflammation and improves function during aging and following chemotherapy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Piccolantonio+A%22">Piccolantonio A</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Altulea+A%22">Altulea A</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Joshi+T%22">Joshi T</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pagliarin+F%22">Pagliarin F</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Di+Palma+M%22">Di Palma M</searchLink>; Department of Biomedical Sciences, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Lin+Y%22">Lin Y</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mackedenski+S%22">Mackedenski S</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ustyantsev+K%22">Ustyantsev K</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Jager+C%22">Jager C</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Berezikov+E%22">Berezikov E</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Demaria+M%22">Demaria M</searchLink>; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Groningent, the Netherlands. m.demaria@umcg.nl. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101773306%22">Nature aging</searchLink> [Nat Aging] 2026 Jul 17. <i>Date of Electronic Publication: </i>2026 Jul 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+US%22">Nature Publishing Group US </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101773306 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2662-8465 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226628465%22">26628465 </searchLink><i>NLM ISO Abbreviation: </i>Nat Aging <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42469443 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s43587-026-01168-1 Languages: – Code: eng Text: English Titles: – TitleFull: Disruption of CDK4/6-RARα-NF-κB axis attenuates senescence-associated inflammation and improves function during aging and following chemotherapy. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang B – PersonEntity: Name: NameFull: Piccolantonio A – PersonEntity: Name: NameFull: Altulea A – PersonEntity: Name: NameFull: Huang M – PersonEntity: Name: NameFull: Joshi T – PersonEntity: Name: NameFull: Pagliarin F – PersonEntity: Name: NameFull: Di Palma M – PersonEntity: Name: NameFull: Lin Y – PersonEntity: Name: NameFull: Mackedenski S – PersonEntity: Name: NameFull: Ustyantsev K – PersonEntity: Name: NameFull: Jager C – PersonEntity: Name: NameFull: Berezikov E – PersonEntity: Name: NameFull: Demaria M IsPartOfRelationships: – BibEntity: Dates: – D: 17 M: 07 Text: 2026 Jul 17 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2662-8465 Titles: – TitleFull: Nature aging Type: main |
| ResultId | 1 |