Diet quality and depressive symptoms in older adults, assessing the effect modification by genetic predisposition and low-grade inflammation: a target trial emulation.

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Title: Diet quality and depressive symptoms in older adults, assessing the effect modification by genetic predisposition and low-grade inflammation: a target trial emulation.
Authors: Mengist B; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia. b.miteku@deakin.edu.au.; College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia. b.miteku@deakin.edu.au., Davoodian N; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia., Lotfaliany M; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia., Pasco JA; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia.; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Agustini B; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia., Forbes M; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia., Marx W; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia., Yu C; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Neumann JT; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Department of Cardiology, University Heart & Vascular Center, Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Lübeck, Hamburg, Germany., Lacaze P; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Owen AJ; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., McNeil JJ; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Woods RL; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Berk M; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia., Mohebbi M; Deakin Institute for Mental and Physical Health and Clinical Translation (Deakin IMPACT), School of Medicine, Deakin University and Barwon Health, Geelong, VIC, Australia.; Biostatistics Unit, Faculty of Health, Deakin University, Geelong, VIC, Australia.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jul 17. Date of Electronic Publication: 2026 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5578
DOI:10.1038/s41380-026-03762-6