Plasma metabolomic signatures of heterogeneous multimorbidity trajectories in ageing: a population-based cohort study.

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Title: Plasma metabolomic signatures of heterogeneous multimorbidity trajectories in ageing: a population-based cohort study.
Authors: Toki R; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. rtoki@keio.jp., Iba C; Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan., Omoto Y; Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan., Matsumoto M; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Iida M; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Edagawa S; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Harada S; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Hirata A; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Miyagawa N; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Miyake A; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Hirayama A; Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan., Sugimoto M; Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan., Sato A; Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan., Amano K; Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan., Soga T; Human Biology-Microbiome-Quantum Research Center, Keio University, Tsuruoka, Yamagata, Japan., Arakawa K; Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan., Takebayashi T; Department of Preventive Medicine and Public Health, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.; Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Source: GeroScience [Geroscience] 2026 Jul 18. Date of Electronic Publication: 2026 Jul 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2509-2723
DOI:10.1007/s11357-026-02408-3