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Age-related differences in the presentation, management, and outcomes of lower gastrointestinal bleeding: a retrospective multinational cohort study.

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Title: Age-related differences in the presentation, management, and outcomes of lower gastrointestinal bleeding: a retrospective multinational cohort study.
Authors: Vara-Luiz F; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal., Palma C; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal., Mascarenhas P; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal., Tham TC; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom., Arvanitakis M; Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, Hopital Erasme, Hopital Universitaire de Bruxelles, ULB, Brussels, Belgium., Rodriguez-de-Santiago E; Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain., Pedroto I; Gastroenterology Department, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal., Simas D; Gastroenterology Department, Hospital de Santo André, Unidade Local de Saúde da Região de Leiria, Leiria, Portugal., Radaelli F; Gastroenterology Department, Valduce Hospital, Como, Italy., Camus M; Sorbonne University & CRSA (Centre de Recherche Saint Antoine), Endoscopy Unit, Saint Antoine Paris Hospital (APHP), Paris, France., Gkolfakis P; Department of Gastroenterology, Konstantopoulio-Patision General Hospital, Athens, Greece.; 2nd Department of Gastroenterology, Medical School, National and Kapodastrian University of Athens, Attikon University General Hospital, Athens, Greece., Triantafyllou K; 2nd Department of Gastroenterology, Medical School, National and Kapodastrian University of Athens, Attikon University General Hospital, Athens, Greece., Fabbri C; Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena, AUSL Romagna, Italy., Patita M; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal., Tan E; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom., Campbell E; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom., Smyth M; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom., Beattie H; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom., Seeruthun R; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom., Hadefi A; Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, Hopital Erasme, Hopital Universitaire de Bruxelles, ULB, Brussels, Belgium., Rodríguez-Francisco G; Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Madrid, Spain., Paulo JP; Gastroenterology Department, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal., Gonçalves L; Gastroenterology Department, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal., Caetano I; Gastroenterology Department, Hospital de Santo André, Unidade Local de Saúde da Região de Leiria, Leiria, Portugal., Savino A; Gastroenterology Department, Valduce Hospital, Como, Italy., Goudot M; Service de Gastroentérologie, CHU Nimes, France., Panagaki A; Department of Gastroenterology, Konstantopoulio-Patision General Hospital, Athens, Greece., Koukoulioti E; 2nd Department of Gastroenterology, Medical School, National and Kapodastrian University of Athens, Attikon University General Hospital, Athens, Greece., Nikolaki M; 2nd Department of Gastroenterology, Medical School, National and Kapodastrian University of Athens, Attikon University General Hospital, Athens, Greece., Gibiino G; Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena, AUSL Romagna, Italy., Gattuso A; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Mendes I; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal., Piçarra F; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal., Fonseca J; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.
Source: The Lancet regional health. Europe [Lancet Reg Health Eur] 2026 Jul 09; Vol. 68, pp. 101775. Date of Electronic Publication: 2026 Jul 09 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: [Oxford] Country of Publication: England NLM ID: 101777707 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-7762 (Electronic) Linking ISSN: 26667762 NLM ISO Abbreviation: Lancet Reg Health Eur Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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  Data: Age-related differences in the presentation, management, and outcomes of lower gastrointestinal bleeding: a retrospective multinational cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Vara-Luiz+F%22">Vara-Luiz F</searchLink>; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.<br /><searchLink fieldCode="AU" term="%22Palma+C%22">Palma C</searchLink>; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.<br /><searchLink fieldCode="AU" term="%22Mascarenhas+P%22">Mascarenhas P</searchLink>; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.<br /><searchLink fieldCode="AU" term="%22Tham+TC%22">Tham TC</searchLink>; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom.<br /><searchLink fieldCode="AU" term="%22Arvanitakis+M%22">Arvanitakis M</searchLink>; Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, Hopital Erasme, Hopital Universitaire de Bruxelles, ULB, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Rodriguez-de-Santiago+E%22">Rodriguez-de-Santiago E</searchLink>; Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Pedroto+I%22">Pedroto I</searchLink>; Gastroenterology Department, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Simas+D%22">Simas D</searchLink>; Gastroenterology Department, Hospital de Santo André, Unidade Local de Saúde da Região de Leiria, Leiria, Portugal.<br /><searchLink fieldCode="AU" term="%22Radaelli+F%22">Radaelli F</searchLink>; Gastroenterology Department, Valduce Hospital, Como, Italy.<br /><searchLink fieldCode="AU" term="%22Camus+M%22">Camus M</searchLink>; Sorbonne University & CRSA (Centre de Recherche Saint Antoine), Endoscopy Unit, Saint Antoine Paris Hospital (APHP), Paris, France.<br /><searchLink fieldCode="AU" term="%22Gkolfakis+P%22">Gkolfakis P</searchLink>; Department of Gastroenterology, Konstantopoulio-Patision General Hospital, Athens, Greece.; 2nd Department of Gastroenterology, Medical School, National and Kapodastrian University of Athens, Attikon University General Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Triantafyllou+K%22">Triantafyllou K</searchLink>; 2nd Department of Gastroenterology, Medical School, National and Kapodastrian University of Athens, Attikon University General Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Fabbri+C%22">Fabbri C</searchLink>; Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena, AUSL Romagna, Italy.<br /><searchLink fieldCode="AU" term="%22Patita+M%22">Patita M</searchLink>; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.<br /><searchLink fieldCode="AU" term="%22Tan+E%22">Tan E</searchLink>; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom.<br /><searchLink fieldCode="AU" term="%22Campbell+E%22">Campbell E</searchLink>; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom.<br /><searchLink fieldCode="AU" term="%22Smyth+M%22">Smyth M</searchLink>; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom.<br /><searchLink fieldCode="AU" term="%22Beattie+H%22">Beattie H</searchLink>; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom.<br /><searchLink fieldCode="AU" term="%22Seeruthun+R%22">Seeruthun R</searchLink>; Gastroenterology Department, Ulster Hospital, Belfast, Northern Ireland, United Kindgom.<br /><searchLink fieldCode="AU" term="%22Hadefi+A%22">Hadefi A</searchLink>; Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, Hopital Erasme, Hopital Universitaire de Bruxelles, ULB, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Francisco+G%22">Rodríguez-Francisco G</searchLink>; Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Paulo+JP%22">Paulo JP</searchLink>; Gastroenterology Department, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Gonçalves+L%22">Gonçalves L</searchLink>; Gastroenterology Department, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Caetano+I%22">Caetano I</searchLink>; Gastroenterology Department, Hospital de Santo André, Unidade Local de Saúde da Região de Leiria, Leiria, Portugal.<br /><searchLink fieldCode="AU" term="%22Savino+A%22">Savino A</searchLink>; Gastroenterology Department, Valduce Hospital, Como, Italy.<br /><searchLink fieldCode="AU" term="%22Goudot+M%22">Goudot M</searchLink>; Service de Gastroentérologie, CHU Nimes, France.<br /><searchLink fieldCode="AU" term="%22Panagaki+A%22">Panagaki A</searchLink>; Department of Gastroenterology, Konstantopoulio-Patision General Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Koukoulioti+E%22">Koukoulioti E</searchLink>; 2nd Department of Gastroenterology, Medical School, National and Kapodastrian University of Athens, Attikon University General Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Nikolaki+M%22">Nikolaki M</searchLink>; 2nd Department of Gastroenterology, Medical School, National and Kapodastrian University of Athens, Attikon University General Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Gibiino+G%22">Gibiino G</searchLink>; Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena, AUSL Romagna, Italy.<br /><searchLink fieldCode="AU" term="%22Gattuso+A%22">Gattuso A</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Mendes+I%22">Mendes I</searchLink>; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.<br /><searchLink fieldCode="AU" term="%22Piçarra+F%22">Piçarra F</searchLink>; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.<br /><searchLink fieldCode="AU" term="%22Fonseca+J%22">Fonseca J</searchLink>; Gastroenterology Department, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.; Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.
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  Data: <searchLink fieldCode="JN" term="%22101777707%22">The Lancet regional health. Europe</searchLink> [Lancet Reg Health Eur] 2026 Jul 09; Vol. 68, pp. 101775. <i>Date of Electronic Publication: </i>2026 Jul 09 (<i>Print Publication: </i>2026).
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