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Histone Acetylation Differentially Modulates CTCF-CTCF Loops and Intra-TAD Interactions.

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Title: Histone Acetylation Differentially Modulates CTCF-CTCF Loops and Intra-TAD Interactions.
Authors: Smith RG; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Department of Biology, Temple University, Philadelphia, PA, USA., Fu Y; Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Schiela KL; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Department of Biology, Temple University, Philadelphia, PA, USA., Dautle M; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Department of Biology, Temple University, Philadelphia, PA, USA., Williams RA; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Biostatitics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA, USA., Wilson HM; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Department of Biology, Temple University, Philadelphia, PA, USA., Azadegan C; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Program in Molecular and Cellular Biology and Genetics, Graduate School of Biomedical Sciences and Professional Studies, Drexel University College of Medicine, Philadelphia, PA, USA., Whetstine JR; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA., Dekker J; Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA. job.dekker@umassmed.edu.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. job.dekker@umassmed.edu., Liu Y; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA. yu.liu@fccc.edu.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA. yu.liu@fccc.edu.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA. yu.liu@fccc.edu.; Biostatitics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA, USA. yu.liu@fccc.edu.
Source: Nature communications [Nat Commun] 2026 Jul 20; Vol. 17 (1). Date of Electronic Publication: 2026 Jul 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Histone Acetylation Differentially Modulates CTCF-CTCF Loops and Intra-TAD Interactions.
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  Data: <searchLink fieldCode="AU" term="%22Smith+RG%22">Smith RG</searchLink>; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Department of Biology, Temple University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fu+Y%22">Fu Y</searchLink>; Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Schiela+KL%22">Schiela KL</searchLink>; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Department of Biology, Temple University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dautle+M%22">Dautle M</searchLink>; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Department of Biology, Temple University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Williams+RA%22">Williams RA</searchLink>; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Biostatitics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+HM%22">Wilson HM</searchLink>; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Department of Biology, Temple University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Azadegan+C%22">Azadegan C</searchLink>; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.; Program in Molecular and Cellular Biology and Genetics, Graduate School of Biomedical Sciences and Professional Studies, Drexel University College of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Whetstine+JR%22">Whetstine JR</searchLink>; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dekker+J%22">Dekker J</searchLink>; Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA. job.dekker@umassmed.edu.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. job.dekker@umassmed.edu.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA. yu.liu@fccc.edu.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA. yu.liu@fccc.edu.; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA. yu.liu@fccc.edu.; Biostatitics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA, USA. yu.liu@fccc.edu.
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