A kinetically inert platinum antitumor agent overcomes mutant p53-driven chemoresistance via oxidative stress-mediated DNA damage.
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| Title: | A kinetically inert platinum antitumor agent overcomes mutant p53-driven chemoresistance via oxidative stress-mediated DNA damage. |
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| Authors: | Chakraborty S; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India., Shenoy PS; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India., Nath S; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India., Panda TR; Laboratory of Medicinal Chemistry and Cell Biology, Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Navy Nagar, 400005, Mumbai, India., Bhat A; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Department of Biology, Indian Institute of Science Education and Research, Tirupati, Andhra Pradesh, 517619, India., Sakpal A; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India., Mehrotra M; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India., Singh P; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India., Patra M; Laboratory of Medicinal Chemistry and Cell Biology, Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Navy Nagar, 400005, Mumbai, India., Ray P; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India. pray@actrec.gov.in.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India. pray@actrec.gov.in. |
| Source: | Medical oncology (Northwood, London, England) [Med Oncol] 2026 Jul 22; Vol. 43 (9). Date of Electronic Publication: 2026 Jul 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42484733 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A kinetically inert platinum antitumor agent overcomes mutant p53-driven chemoresistance via oxidative stress-mediated DNA damage. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chakraborty+S%22">Chakraborty S</searchLink>; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India.<br /><searchLink fieldCode="AU" term="%22Shenoy+PS%22">Shenoy PS</searchLink>; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India.<br /><searchLink fieldCode="AU" term="%22Nath+S%22">Nath S</searchLink>; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India.<br /><searchLink fieldCode="AU" term="%22Panda+TR%22">Panda TR</searchLink>; Laboratory of Medicinal Chemistry and Cell Biology, Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Navy Nagar, 400005, Mumbai, India.<br /><searchLink fieldCode="AU" term="%22Bhat+A%22">Bhat A</searchLink>; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Department of Biology, Indian Institute of Science Education and Research, Tirupati, Andhra Pradesh, 517619, India.<br /><searchLink fieldCode="AU" term="%22Sakpal+A%22">Sakpal A</searchLink>; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.<br /><searchLink fieldCode="AU" term="%22Mehrotra+M%22">Mehrotra M</searchLink>; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India.<br /><searchLink fieldCode="AU" term="%22Singh+P%22">Singh P</searchLink>; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India.<br /><searchLink fieldCode="AU" term="%22Patra+M%22">Patra M</searchLink>; Laboratory of Medicinal Chemistry and Cell Biology, Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Navy Nagar, 400005, Mumbai, India.<br /><searchLink fieldCode="AU" term="%22Ray+P%22">Ray P</searchLink>; Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, 410210, India. pray@actrec.gov.in.; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India. pray@actrec.gov.in. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229435512%22">Medical oncology (Northwood, London, England)</searchLink> [Med Oncol] 2026 Jul 22; Vol. 43 (9). <i>Date of Electronic Publication: </i>2026 Jul 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9435512 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-131X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213570560%22">13570560 </searchLink><i>NLM ISO Abbreviation: </i>Med Oncol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42484733 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s12032-026-03348-w Languages: – Code: eng Text: English Titles: – TitleFull: A kinetically inert platinum antitumor agent overcomes mutant p53-driven chemoresistance via oxidative stress-mediated DNA damage. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chakraborty S – PersonEntity: Name: NameFull: Shenoy PS – PersonEntity: Name: NameFull: Nath S – PersonEntity: Name: NameFull: Panda TR – PersonEntity: Name: NameFull: Bhat A – PersonEntity: Name: NameFull: Sakpal A – PersonEntity: Name: NameFull: Mehrotra M – PersonEntity: Name: NameFull: Singh P – PersonEntity: Name: NameFull: Patra M – PersonEntity: Name: NameFull: Ray P IsPartOfRelationships: – BibEntity: Dates: – D: 22 M: 07 Text: 2026 Jul 22 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1559-131X Numbering: – Type: volume Value: 43 – Type: issue Value: 9 Titles: – TitleFull: Medical oncology (Northwood, London, England) Type: main |
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