Intensive Blood-Pressure Control for the Prevention of Major Cardiovascular Events in Patients with Type 2 Diabetes: Rationale, Design and Baseline Characteristics of the OPTIMAL-DIABETES Randomized Trial.
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| Title: | Intensive Blood-Pressure Control for the Prevention of Major Cardiovascular Events in Patients with Type 2 Diabetes: Rationale, Design and Baseline Characteristics of the OPTIMAL-DIABETES Randomized Trial. |
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| Authors: | Santo K; Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address: karla.santo@einstein.br., Martins E; Hospital Israelita Albert Einstein, São Paulo, Brazil., Silva GS; Hospital Israelita Albert Einstein, São Paulo, Brazil; Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil., Guimarães PO; Hospital Israelita Albert Einstein, São Paulo, Brazil., Tavares CAM; Hospital Israelita Albert Einstein, São Paulo, Brazil; Instituto do Coração (InCor), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Brainer J; Hospital Israelita Albert Einstein, São Paulo, Brazil; Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil., Monfardini F; Hospital Israelita Albert Einstein, São Paulo, Brazil., Nieri J; Hospital Israelita Albert Einstein, São Paulo, Brazil., Assis SRL; Hospital Israelita Albert Einstein, São Paulo, Brazil., Felício JS; João de Barros Barreto University Hospital, Federal University of Pará, Belém, Brazil., Silveira FS; Centro de Pesquisa Clínica do Coração, Aracaju, Brazil., Feitosa ADM; Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco, Recife, Brazil., Hissa MN; Centro de Pesquisas em Diabetes e Doenças Endócrino-Metabólicas /Clínica Popular Endocrinologia, Fortaleza, Brazil., Sobral-Filho DC; Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco, Recife, Brazil., Vilela-Martin JF; State Medicine School of São José do Rio Preto (FAMERP), São José do Rio Preto, Brazil., Cestario EES; State Medicine School of São José do Rio Preto (FAMERP), São José do Rio Preto, Brazil; University Center of Votuporanga (UNIFEV), Votuporanga, Brazil., Yugar-Toledo JC; State Medicine School of São José do Rio Preto (FAMERP), São José do Rio Preto, Brazil., Batista MC; Hospital Israelita Albert Einstein, São Paulo, Brazil; Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil., Turatti L; Hospital Israelita Albert Einstein, São Paulo, Brazil., Brandão AA; Faculty of Medical Sciences, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil., Barroso WS; Hypertension Unit, Medicine School, Federal University of Goiás, Goiânia, Brazil., Sposito AC; Clinical Research Center, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil., Drager LF; Instituto do Coração (InCor), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil; Unidade de Hipertensão, Disciplina de Nefrologia, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Bortolotto LA; Instituto do Coração (InCor), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Fuchs SC; Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil., Franken M; Hospital Israelita Albert Einstein, São Paulo, Brazil., Lemos PA; Hospital Israelita Albert Einstein, São Paulo, Brazil; Faculty of Health Sciences, Universidad Autónoma de Chile, Providencia, Chile., Santos RD; Hospital Israelita Albert Einstein, São Paulo, Brazil; Instituto do Coração (InCor), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Rodgers A; George Institute for Global Health, Sydney, Australia., Whelton PK; Tulane University Celia Scott Weatherhead School of Public Health and Tropical Medicine, New Orleans, USA., Fuchs FD; Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil., Berwanger O; George Institute for Global Health UK, London, United Kingdom; Imperial College London, London, United Kingdom. |
| Source: | American heart journal [Am Heart J] 2026 Jul 24, pp. 107545. Date of Electronic Publication: 2026 Jul 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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