A novel topical nitroglycerin-lidocaine combination for procedural pain management and rapid cannulation in neonates: results from a randomized controlled clinical trial.

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Title: A novel topical nitroglycerin-lidocaine combination for procedural pain management and rapid cannulation in neonates: results from a randomized controlled clinical trial.
Authors: Saghafi F; Traditional Pharmacy and Pharmaceutical Sciences Research Center, and Department ofClinical Pharmacy, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran., Mohammadi F; Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences and Health Services, Shiraz, Iran., Esmaeili M; Pharmaceutical Sciences Research Center, School of Pharmacy, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran., Shadkam MN; Mother and newborn Health Research Center, School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran., Sahebnasagh A; Clinical Research Center, Department of Internal Medicine, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran. masoomehsahebnasagh@gmail.com.; Fellowship of Critical Care Pharmacotherapy, Department of Internal Medicine, Faculty of Medicine, Associate Professor of Clinical Pharmacy, North Khorasan University of Medical Sciences, Bojnourd, Iran. masoomehsahebnasagh@gmail.com.; Imam Ali Hospital, Shahriar Street, North Khorasan Province, Bojnurd, Iran. masoomehsahebnasagh@gmail.com.
Source: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2026 Jul 25; Vol. 82 (8). Date of Electronic Publication: 2026 Jul 25.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1041 (Electronic) Linking ISSN: 00316970 NLM ISO Abbreviation: Eur J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel topical nitroglycerin-lidocaine combination for procedural pain management and rapid cannulation in neonates: results from a randomized controlled clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Saghafi+F%22">Saghafi F</searchLink>; Traditional Pharmacy and Pharmaceutical Sciences Research Center, and Department ofClinical Pharmacy, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.<br /><searchLink fieldCode="AU" term="%22Mohammadi+F%22">Mohammadi F</searchLink>; Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences and Health Services, Shiraz, Iran.<br /><searchLink fieldCode="AU" term="%22Esmaeili+M%22">Esmaeili M</searchLink>; Pharmaceutical Sciences Research Center, School of Pharmacy, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.<br /><searchLink fieldCode="AU" term="%22Shadkam+MN%22">Shadkam MN</searchLink>; Mother and newborn Health Research Center, School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.<br /><searchLink fieldCode="AU" term="%22Sahebnasagh+A%22">Sahebnasagh A</searchLink>; Clinical Research Center, Department of Internal Medicine, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran. masoomehsahebnasagh@gmail.com.; Fellowship of Critical Care Pharmacotherapy, Department of Internal Medicine, Faculty of Medicine, Associate Professor of Clinical Pharmacy, North Khorasan University of Medical Sciences, Bojnourd, Iran. masoomehsahebnasagh@gmail.com.; Imam Ali Hospital, Shahriar Street, North Khorasan Province, Bojnurd, Iran. masoomehsahebnasagh@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%221256165%22">European journal of clinical pharmacology</searchLink> [Eur J Clin Pharmacol] 2026 Jul 25; Vol. 82 (8). <i>Date of Electronic Publication: </i>2026 Jul 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>1256165 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1041 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200316970%22">00316970 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Clin Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00228-026-04146-z
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              Text: 2026 Jul 25
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