Systematic Benchmarking of CRISPR-Cas9 Off-Target Prediction Tools Reveals Limitations and Implications for Preclinical Assessment.
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| Title: | Systematic Benchmarking of CRISPR-Cas9 Off-Target Prediction Tools Reveals Limitations and Implications for Preclinical Assessment. |
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| Authors: | Kaufmann MM; Institute for Transfusion Medicine and Gene Therapy, Medical Center-University of Freiburg, Freiburg, Germany., Hackenberg M; Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Jobson Pargeter W; Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg, Germany., Backofen R; Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg, Germany.; Signalling Research Centre CIBSS, University of Freiburg, Freiburg, Germany., Binder H; Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Cathomen T; Institute for Transfusion Medicine and Gene Therapy, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Cell and Gene Therapy, Freiburg, Germany. |
| Source: | Human gene therapy [Hum Gene Ther] 2026 Jul 26, pp. 10430342261466407. Date of Electronic Publication: 2026 Jul 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7422 (Electronic) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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