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Blocking interleukin 33 reduces joint, systemic, and lung inflammatory responses in the combined collagen-induced arthritis-inhalant endotoxin exposure model.

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Title: Blocking interleukin 33 reduces joint, systemic, and lung inflammatory responses in the combined collagen-induced arthritis-inhalant endotoxin exposure model.
Authors: Poole JA; Division of Allergy and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska. Electronic address: japoole@unmc.edu., Larsen JL; Division of Allergy and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska., Thiele GM; Division of Rheumatology and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Veterans Affairs Nebraska-Western Iowa Health Care System, Research Service, Omaha, Nebraska., Wyatt TA; Veterans Affairs Nebraska-Western Iowa Health Care System, Research Service, Omaha, Nebraska; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Department of Environmental, Agricultural and Occupational Health, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska., Nelson AJ; Division of Allergy and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska., Duryee MJ; Division of Rheumatology and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Veterans Affairs Nebraska-Western Iowa Health Care System, Research Service, Omaha, Nebraska., Gleason AM; Division of Allergy and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska., Schanze OW; Division of Allergy and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska., Schwab AD; Division of Allergy and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska., Dickinson JD; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska., Mosley D; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska., Lush M; Department of Anesthesiology, University of Nebraska Medical Center, Omaha, Nebraska., Wang HJ; Department of Anesthesiology, University of Nebraska Medical Center, Omaha, Nebraska., Cohen ES; Bioscience Asthma, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., England BR; Division of Rheumatology and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Veterans Affairs Nebraska-Western Iowa Health Care System, Research Service, Omaha, Nebraska., Mikuls TR; Division of Rheumatology and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska; Veterans Affairs Nebraska-Western Iowa Health Care System, Research Service, Omaha, Nebraska.
Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2026 Jul 09, pp. 104983. Date of Electronic Publication: 2026 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE
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  Data: Blocking interleukin 33 reduces joint, systemic, and lung inflammatory responses in the combined collagen-induced arthritis-inhalant endotoxin exposure model.
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