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Baseline Disease Characteristics and Platinum Sensitivity as Predictors of Outcomes in Sequential Therapy with Platinum-Based Chemotherapy, Avelumab Maintenance, and Enfortumab Vedotin in Advanced Urothelial Carcinoma (ARON-2EV Study).

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Title: Baseline Disease Characteristics and Platinum Sensitivity as Predictors of Outcomes in Sequential Therapy with Platinum-Based Chemotherapy, Avelumab Maintenance, and Enfortumab Vedotin in Advanced Urothelial Carcinoma (ARON-2EV Study).
Authors: Rizzo M; Medical Oncology Unit, Azienda Ospedaliera Universitaria Consorziale Policlinico di Bari, piazza Giulio Cesare 11, 70124, Bari, Italy. rizzo.mimma@gmail.com., Buti S; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Oncology Unit, University Hospital of Parma, Parma, Italy.; ARON Research Foundation ETS, Macerata, Italy., Fiala O; ARON Research Foundation ETS, Macerata, Italy.; Department of Oncology and Radiotherapeutics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Incorvaia L; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, Palermo, Italy., Molina-Cerrillo J; ARON Research Foundation ETS, Macerata, Italy.; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain., Bourlon MT; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Fukuokaya W; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan., Urabe F; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan., Park SH; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Mayrhofer K; Department of Internal Medicine, Centre for Oncology and Haematology, Vienna Healthcare Group, Ottakring, Vienna, Austria., Pichler R; Department of Urology, Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria., Niedersuess-Beke D; Department of Internal Medicine, Centre for Oncology and Haematology, Vienna Healthcare Group, Ottakring, Vienna, Austria., Taha T; Royal Marsden NHS Foundation Trust, London, UK., Büttner T; Department of Urology, University Hospital Bonn, Bonn, Germany., Bamias A; 2nd Propaedeutic Department of Internal Medicine, ATTIKON University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Seront E; Department of Medical Oncology, Institut Roi Albert II, Saint-Luc University Hospital, UCLouvain, Brussels, Belgium., Santini D; Department of Medical-Surgery Sciences and Biotechnologies, Policlinico Umberto I, University of Rome, Rome, Italy., Stumbo L; Department of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico of Rome, Rome, Italy., Rodriguez-Vida A; Medical Oncology Department, Hospital del Mar, Barcelona, Spain., Massari F; ARON Research Foundation ETS, Macerata, Italy.; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy., Monteiro FSM; ARON Research Foundation ETS, Macerata, Italy.; Oncology and Hematology Department, Hospital Sírio Libanês, Brasília, Brazil.; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil., Soares A; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Oncology Unit, Einstein Hospital Israelita, São Paulo, SP, Brazil., Grande E; Department of Medical Oncology, Quirónsalud Madrid, Madrid, Spain.; Facultad de Medicina, Universidad Francisco de Vitoria, Pozuelo de Alarcón, Spain., Santoni M; ARON Research Foundation ETS, Macerata, Italy.; Medical Oncology Unit, Macerata Hospital, Macerata, Italy.
Source: Targeted oncology [Target Oncol] 2026 Jul 29. Date of Electronic Publication: 2026 Jul 29.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag France Country of Publication: France NLM ID: 101270595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1776-260X (Electronic) Linking ISSN: 17762596 NLM ISO Abbreviation: Target Oncol Subsets: MEDLINE
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  Data: Baseline Disease Characteristics and Platinum Sensitivity as Predictors of Outcomes in Sequential Therapy with Platinum-Based Chemotherapy, Avelumab Maintenance, and Enfortumab Vedotin in Advanced Urothelial Carcinoma (ARON-2EV Study).
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  Data: <searchLink fieldCode="AU" term="%22Rizzo+M%22">Rizzo M</searchLink>; Medical Oncology Unit, Azienda Ospedaliera Universitaria Consorziale Policlinico di Bari, piazza Giulio Cesare 11, 70124, Bari, Italy. rizzo.mimma@gmail.com.<br /><searchLink fieldCode="AU" term="%22Buti+S%22">Buti S</searchLink>; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Oncology Unit, University Hospital of Parma, Parma, Italy.; ARON Research Foundation ETS, Macerata, Italy.<br /><searchLink fieldCode="AU" term="%22Fiala+O%22">Fiala O</searchLink>; ARON Research Foundation ETS, Macerata, Italy.; Department of Oncology and Radiotherapeutics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Incorvaia+L%22">Incorvaia L</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Molina-Cerrillo+J%22">Molina-Cerrillo J</searchLink>; ARON Research Foundation ETS, Macerata, Italy.; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bourlon+MT%22">Bourlon MT</searchLink>; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Fukuokaya+W%22">Fukuokaya W</searchLink>; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Urabe+F%22">Urabe F</searchLink>; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Park+SH%22">Park SH</searchLink>; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Mayrhofer+K%22">Mayrhofer K</searchLink>; Department of Internal Medicine, Centre for Oncology and Haematology, Vienna Healthcare Group, Ottakring, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Pichler+R%22">Pichler R</searchLink>; Department of Urology, Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Niedersuess-Beke+D%22">Niedersuess-Beke D</searchLink>; Department of Internal Medicine, Centre for Oncology and Haematology, Vienna Healthcare Group, Ottakring, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Taha+T%22">Taha T</searchLink>; Royal Marsden NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Büttner+T%22">Büttner T</searchLink>; Department of Urology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Bamias+A%22">Bamias A</searchLink>; 2nd Propaedeutic Department of Internal Medicine, ATTIKON University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Seront+E%22">Seront E</searchLink>; Department of Medical Oncology, Institut Roi Albert II, Saint-Luc University Hospital, UCLouvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Santini+D%22">Santini D</searchLink>; Department of Medical-Surgery Sciences and Biotechnologies, Policlinico Umberto I, University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Stumbo+L%22">Stumbo L</searchLink>; Department of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Vida+A%22">Rodriguez-Vida A</searchLink>; Medical Oncology Department, Hospital del Mar, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Massari+F%22">Massari F</searchLink>; ARON Research Foundation ETS, Macerata, Italy.; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Monteiro+FSM%22">Monteiro FSM</searchLink>; ARON Research Foundation ETS, Macerata, Italy.; Oncology and Hematology Department, Hospital Sírio Libanês, Brasília, Brazil.; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Soares+A%22">Soares A</searchLink>; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Oncology Unit, Einstein Hospital Israelita, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Grande+E%22">Grande E</searchLink>; Department of Medical Oncology, Quirónsalud Madrid, Madrid, Spain.; Facultad de Medicina, Universidad Francisco de Vitoria, Pozuelo de Alarcón, Spain.<br /><searchLink fieldCode="AU" term="%22Santoni+M%22">Santoni M</searchLink>; ARON Research Foundation ETS, Macerata, Italy.; Medical Oncology Unit, Macerata Hospital, Macerata, Italy.
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