Synthesis and biological evaluation of Phorbazole D analogues identify IO-5a as a promoter of hUC-MSC chondrogenic differentiation.

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Title: Synthesis and biological evaluation of Phorbazole D analogues identify IO-5a as a promoter of hUC-MSC chondrogenic differentiation.
Authors: Wang AZ; School of Life Science and Technology, Tongji University, Shanghai, 200092, China.; Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China., Liu XM; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.; Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai, 264117, Shandong, China., Zhang LM; School of Life Science and Technology, Tongji University, Shanghai, 200092, China., Fu LL; School of Life Science and Technology, Tongji University, Shanghai, 200092, China., Li P; School of Life Science and Technology, Tongji University, Shanghai, 200092, China., Zhang JP; School of Medicine, Tongji University, Shanghai, 200092, China. zhangjieping@tongji.edu.cn., Han H; School of Medicine, Tongji University, Shanghai, 200092, China. hanhua@tongji.edu.cn.
Source: Molecular diversity [Mol Divers] 2026 Jul 30. Date of Electronic Publication: 2026 Jul 30.
Publication Type: Journal Article
Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-501X
DOI:10.1007/s11030-026-11683-3