A cortical insula-orbitofrontal circuit drives stress-induced dopamine system dysfunction.

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Title: A cortical insula-orbitofrontal circuit drives stress-induced dopamine system dysfunction.
Authors: Yang OJ; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA. yango@livemail.uthscsa.edu.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA. yango@livemail.uthscsa.edu., Reiley HB; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA.; Department of Pharmacology and Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, 37232, USA., Boley AM; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA., Perez SM; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA., Lodge DJ; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jul 30. Date of Electronic Publication: 2026 Jul 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5578
DOI:10.1038/s41380-026-03791-1