A cortical insula-orbitofrontal circuit drives stress-induced dopamine system dysfunction.

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Title: A cortical insula-orbitofrontal circuit drives stress-induced dopamine system dysfunction.
Authors: Yang OJ; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA. yango@livemail.uthscsa.edu.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA. yango@livemail.uthscsa.edu., Reiley HB; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA.; Department of Pharmacology and Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, 37232, USA., Boley AM; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA., Perez SM; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA., Lodge DJ; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jul 30. Date of Electronic Publication: 2026 Jul 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yang+OJ%22">Yang OJ</searchLink>; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA. yango@livemail.uthscsa.edu.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA. yango@livemail.uthscsa.edu.<br /><searchLink fieldCode="AU" term="%22Reiley+HB%22">Reiley HB</searchLink>; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA.; Department of Pharmacology and Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Boley+AM%22">Boley AM</searchLink>; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Perez+SM%22">Perez SM</searchLink>; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.<br /><searchLink fieldCode="AU" term="%22Lodge+DJ%22">Lodge DJ</searchLink>; Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas at San Antonio, San Antonio, TX, 78229, USA.; South Texas Veterans Health Care System, Audie L. Murphy Division, San Antonio, TX, USA.
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        Value: 10.1038/s41380-026-03791-1
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              Text: 2026 Jul 30
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