A critical review of the early clozapine trials published in German and a discussion of the many unresolved issues left by these trials.

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Title: A critical review of the early clozapine trials published in German and a discussion of the many unresolved issues left by these trials.
Authors: Ferrea S; Adult Psychiatry and Psychotherapy, Psychiatric Hospital, University of Zurich, Zurich, Switzerland., de Leon J; Mental Health Research Center, Eastern State Hospital, Lexington, KY, USA.; Biomedical Research Centre in Mental Health Net (CIBERSAM), Santiago Apóstol Hospital, University of the Basque Country, Vitoria, Spain., Baumann P; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly-Lausanne, Switzerland., Benkert O; Department of Psychiatry, University of Mainz, Mainz, Germany., Helmchen H; Charité - Universitätsmedizin Berlin, Berlin, Germany., Correll CU; The Zucker Hillside Hospital, Psychiatry Research, Northwell Health, Glen Oaks, NY, USA.; Department of Psychiatry, Zucker School of Medicine at Northwell/Hofstra, Hempstead, NY, USA.; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany., Schoretsanitis G; Adult Psychiatry and Psychotherapy, Psychiatric Hospital, University of Zurich, Zurich, Switzerland. george.schor@gmail.com.; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly-Lausanne, Switzerland. george.schor@gmail.com.; The Zucker Hillside Hospital, Psychiatry Research, Northwell Health, Glen Oaks, NY, USA. george.schor@gmail.com.; Department of Psychiatry, Zucker School of Medicine at Northwell/Hofstra, Hempstead, NY, USA. george.schor@gmail.com.; Unit of Pharmacogenetics and Clinical Psychopharmacology, Center for Psychiatric Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. george.schor@gmail.com.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Aug 01. Date of Electronic Publication: 2026 Aug 01.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-1912
DOI:10.1007/s00210-026-05742-7