View in EDS HTML Full Text PDF Full Text

Optogenetic tachypacing facilitates burst-induced arrhythmia in stem cell-derived human atrial engineered heart tissue.

Saved in:
Bibliographic Details
Title: Optogenetic tachypacing facilitates burst-induced arrhythmia in stem cell-derived human atrial engineered heart tissue.
Authors: Müller KF; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Pan B; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Institute of Experimental Cardiology, University Hospital Heidelberg, 69120 Heidelberg, Germany., Ridder J; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, 20246 Hamburg, Germany., Schrapers J; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany., Hansen J; Sarcura GmbH, 3400 Klosterneuburg, Austria., Meier TM; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany., Schulz C; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Stüdemann T; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany., Lemme M; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; Nanion Technologies GmbH, 80339 Munich, Germany., Krause J; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Hirt MN; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, 20246 Hamburg, Germany., Stoter AMS; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany., Braren I; Vector Facility, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Spohn M; Bioinformatics Core Facility, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Weinberger F; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Research Group Tissue Engineering and Regenerative Therapies, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain., Fabritz L; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, 20246 Hamburg, Germany., Duan X; Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany.; Department of Neuroscience, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China., Gao S; Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany., Gee CE; Department of Synaptic Neuroscience, Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany., Hansen A; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany., Eschenhagen T; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany., Christ T; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany., Stenzig J; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.
Source: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2026 Aug 04; Vol. 28 (8).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883649 Publication Model: Print Cited Medium: Internet ISSN: 1532-2092 (Electronic) Linking ISSN: 10995129 NLM ISO Abbreviation: Europace Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42611532
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Optogenetic tachypacing facilitates burst-induced arrhythmia in stem cell-derived human atrial engineered heart tissue.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Müller+KF%22">Müller KF</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Pan+B%22">Pan B</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Institute of Experimental Cardiology, University Hospital Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Ridder+J%22">Ridder J</searchLink>; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schrapers+J%22">Schrapers J</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hansen+J%22">Hansen J</searchLink>; Sarcura GmbH, 3400 Klosterneuburg, Austria.<br /><searchLink fieldCode="AU" term="%22Meier+TM%22">Meier TM</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schulz+C%22">Schulz C</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stüdemann+T%22">Stüdemann T</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lemme+M%22">Lemme M</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; Nanion Technologies GmbH, 80339 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Krause+J%22">Krause J</searchLink>; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hirt+MN%22">Hirt MN</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stoter+AMS%22">Stoter AMS</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Braren+I%22">Braren I</searchLink>; Vector Facility, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Spohn+M%22">Spohn M</searchLink>; Bioinformatics Core Facility, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Weinberger+F%22">Weinberger F</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Research Group Tissue Engineering and Regenerative Therapies, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Fabritz+L%22">Fabritz L</searchLink>; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.; Department of Cardiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Duan+X%22">Duan X</searchLink>; Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany.; Department of Neuroscience, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gee+CE%22">Gee CE</searchLink>; Department of Synaptic Neuroscience, Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hansen+A%22">Hansen A</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Eschenhagen+T%22">Eschenhagen T</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Christ+T%22">Christ T</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stenzig+J%22">Stenzig J</searchLink>; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22100883649%22">Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology</searchLink> [Europace] 2026 Aug 04; Vol. 28 (8).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100883649 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-2092 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210995129%22">10995129 </searchLink><i>NLM ISO Abbreviation: </i>Europace <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42611532
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1093/europace/euag158
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Optogenetic tachypacing facilitates burst-induced arrhythmia in stem cell-derived human atrial engineered heart tissue.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Müller KF
      – PersonEntity:
          Name:
            NameFull: Pan B
      – PersonEntity:
          Name:
            NameFull: Ridder J
      – PersonEntity:
          Name:
            NameFull: Schrapers J
      – PersonEntity:
          Name:
            NameFull: Hansen J
      – PersonEntity:
          Name:
            NameFull: Meier TM
      – PersonEntity:
          Name:
            NameFull: Schulz C
      – PersonEntity:
          Name:
            NameFull: Stüdemann T
      – PersonEntity:
          Name:
            NameFull: Lemme M
      – PersonEntity:
          Name:
            NameFull: Krause J
      – PersonEntity:
          Name:
            NameFull: Hirt MN
      – PersonEntity:
          Name:
            NameFull: Stoter AMS
      – PersonEntity:
          Name:
            NameFull: Braren I
      – PersonEntity:
          Name:
            NameFull: Spohn M
      – PersonEntity:
          Name:
            NameFull: Weinberger F
      – PersonEntity:
          Name:
            NameFull: Fabritz L
      – PersonEntity:
          Name:
            NameFull: Duan X
      – PersonEntity:
          Name:
            NameFull: Gao S
      – PersonEntity:
          Name:
            NameFull: Gee CE
      – PersonEntity:
          Name:
            NameFull: Hansen A
      – PersonEntity:
          Name:
            NameFull: Eschenhagen T
      – PersonEntity:
          Name:
            NameFull: Christ T
      – PersonEntity:
          Name:
            NameFull: Stenzig J
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 04
              M: 08
              Text: 2026 Aug 04
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1532-2092
          Numbering:
            – Type: volume
              Value: 28
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
              Type: main
ResultId 1