Functional immune changes are conserved in COVID-19 and trauma patients receiving intensive care.

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Title: Functional immune changes are conserved in COVID-19 and trauma patients receiving intensive care.
Authors: Wood AJT; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia. alexander.wood@health.wa.gov.au.; The Royal Melbourne Hospital, Melbourne, VIC, Australia. alexander.wood@health.wa.gov.au.; Medical School, University of Western Australia, Perth, WA, Australia. alexander.wood@health.wa.gov.au.; Intensive Care Unit, Fiona Stanley Hospital, Perth, WA, Australia. alexander.wood@health.wa.gov.au., Albers GJ; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Cornelissen W; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Maiden JD; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia.; The Royal Melbourne Hospital, Melbourne, VIC, Australia., Cuff DE; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Ashayeripanah M; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Schriek P; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Emery-Corbin SJ; Monash Proteomics & Metabolomics Platform, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Scott NE; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Li S; Computational Sciences Initiative, the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Schröder J; Computational Sciences Initiative, the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Deane AM; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia.; The Royal Melbourne Hospital, Melbourne, VIC, Australia., Villadangos JA; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia. j.villadangos@unimelb.edu.au.; Department of Biochemistry and Pharmacology, University of Melbourne at the Bio21 Molecular Science and Biotechnology Institute, Melbourne, VIC, Australia. j.villadangos@unimelb.edu.au., Cook L; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia. l.cook@unimelb.edu.au.; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia. l.cook@unimelb.edu.au.; Division of Infectious Diseases, University of British Columbia, Vancouver, BC, Canada. l.cook@unimelb.edu.au.
Source: Nature communications [Nat Commun] 2026 Aug 25; Vol. 17 (1). Date of Electronic Publication: 2026 Aug 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-75748-5