Proteasome inhibition alleviates proteinuria in Lmx1b knock-in mice with dysfunctional LIM domains.

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Title: Proteasome inhibition alleviates proteinuria in Lmx1b knock-in mice with dysfunctional LIM domains.
Authors: Hermens J; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany., Lucke L; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany., Pieles O; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany., Maier O; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany., Othmen H; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany., Burghardt T; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany., Schmidt A; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany., Moser M; Max-Planck-Institute of Biochemistry, Department of Molecular Medicine, Martinsried, Germany.; Institute of Experimental Hematology, Technische Universität München, Munich, Germany., Madej MG; Department of Biophysics, University of Regensburg, Regensburg, Germany., Schwartz U; NGS Analysis Center, Faculty of Biology and Pre-Clinical Medicine, University of Regensburg, Regensburg, Germany., Zaparty M; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany., Witzgall R; Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany. ralph.witzgall@vkl.uni-regensburg.de.
Source: Nature communications [Nat Commun] 2026 Sep 11; Vol. 17 (1). Date of Electronic Publication: 2026 Sep 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-77485-1