PLA2G2F/lysoplasmalogen axis links epidermal lipid metabolism to type 2 inflammation and itch in atopic dermatitis.
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| Title: | PLA2G2F/lysoplasmalogen axis links epidermal lipid metabolism to type 2 inflammation and itch in atopic dermatitis. |
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| Authors: | Miki Y; Division of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan.; Graduate School of Biomedical Sciences, Pharmaceutical Sciences, Tokushima University, Tokushima, Japan.; Institute of Photonics and Human Health Frontier, Tokushima University, Tokushima, Japan., Higashisaka N; Division of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan., Inubushi H; Division of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan., Hirabayashi N; Division of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan., Watanabe K; Division of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan., Fukui S; Division of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan., Onitsuka M; Division of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan., Fukaura C; Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Ogawa-Momohara M; Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Tanahashi K; Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Nagasaki Y; Laboratory of Microenvironmental Metabolic Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Division of Physiological Chemistry and Metabolism, Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Takeichi T; Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Nagoya University Institute for Advanced Research, Nagoya, Japan., Akiyama M; Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Dermatology, Shin-yurigaoka General Hospital, Kawasaki, Japan., Murakami M; Laboratory of Microenvironmental Metabolic Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Division of Physiological Chemistry and Metabolism, Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; AMED-CREST, Japan Agency for Medical Research and Development, Tokyo, Japan., Yamamoto K; Division of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan.; PRIME, Japan Agency for Medical Research and Development, Tokyo, Japan. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Sep 07; Vol. 17, pp. 1880255. Date of Electronic Publication: 2026 Sep 07 (Print Publication: 2026). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1880255 |