Inflammasomes: Mechanism of Action, Regulation and Role in Disease
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| Title: | Inflammasomes: Mechanism of Action, Regulation and Role in Disease |
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| Description: | The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1â takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections. |
| Authors: | Mason, Angie |
| Resource Type: | eBook. |
| Subjects: | Inflammation--Immunological aspects |
| Categories: | MEDICAL / Internal Medicine, HEALTH & FITNESS / Diseases & Conditions / General, MEDICAL / Clinical Medicine, MEDICAL / Diseases, MEDICAL / Evidence-Based Medicine |
| Database: | eBook Collection (EBSCOhost) |
| Abstract: | The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1â takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections. |
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| ISBN: | 9781634848916 9781634849111 |
