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Inflammasomes: Mechanism of Action, Regulation and Role in Disease

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Title: Inflammasomes: Mechanism of Action, Regulation and Role in Disease
Description: The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1â takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections.
Authors: Mason, Angie
Resource Type: eBook.
Subjects: Inflammation--Immunological aspects
Categories: MEDICAL / Internal Medicine, HEALTH & FITNESS / Diseases & Conditions / General, MEDICAL / Clinical Medicine, MEDICAL / Diseases, MEDICAL / Evidence-Based Medicine
Database: eBook Collection (EBSCOhost)
FullText Links:
  – Type: ebook-pdf
Text:
  Availability: 0
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DbLabel: eBook Collection (EBSCOhost)
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RelevancyScore: 1070
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
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  Data: Inflammasomes: Mechanism of Action, Regulation and Role in Disease
– Name: Abstract
  Label: Description
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  Data: The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1â takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections.
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  Data: <searchLink fieldCode="AR" term="%22Mason%2C+Angie%22">Mason, Angie</searchLink>
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RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 616.0473
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Inflammation--Immunological aspects
        Type: general
    Titles:
      – TitleFull: Inflammasomes: Mechanism of Action, Regulation and Role in Disease
        Type: main
  BibRelationships:
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      – PersonEntity:
          Name:
            NameFull: Mason, Angie
      – PersonEntity:
          Name:
            NameFull: Mason, Angie
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          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2016
            – D: 28
              M: 06
              Type: profile
              Y: 2016
          Identifiers:
            – Type: isbn-print
              Value: 9781634848916
            – Type: isbn-electronic
              Value: 9781634849111
          Titles:
            – TitleFull: Inflammasomes: Mechanism of Action, Regulation and Role in Disease
              Type: main
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