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Rna Viruses: Host Gene Responses To Infections

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Title: Rna Viruses: Host Gene Responses To Infections
Description: This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small interfering RNA/microRNA-mediated gene silencing pathway, a recently characterized new host defense mechanism against viral infection.Organized into 27 highly accessible and well-illustrated chapters, this volume explores state-of-the-art knowledge of the molecular mechanisms of RNA virus infection and host-virus interactions. This comprehensive compilation of the altered gene expression profiles and signal transduction pathways in host cells in response to the majority of human/animal RNA viruses opens new directions for basic and clinical research on viral pathogenesis, and also provides valuable biomarkers for researchers to select gene targets in the development of diagnostic tests and antiviral therapeutics for a number of infectious diseases.
Authors: Decheng Yang
Resource Type: eBook.
Subjects: RNA interference, RNA viruses, Viral genetics
Categories: MEDICAL / Microbiology, MEDICAL / Infectious Diseases, MEDICAL / Pathology
Database: eBook Collection (EBSCOhost)
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  – Type: ebook-pdf
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Header DbId: nlebk
DbLabel: eBook Collection (EBSCOhost)
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RelevancyScore: 1025
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
PreciseRelevancyScore: 1024.62744140625
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  Data: Rna Viruses: Host Gene Responses To Infections
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  Label: Description
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  Data: This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small interfering RNA/microRNA-mediated gene silencing pathway, a recently characterized new host defense mechanism against viral infection.Organized into 27 highly accessible and well-illustrated chapters, this volume explores state-of-the-art knowledge of the molecular mechanisms of RNA virus infection and host-virus interactions. This comprehensive compilation of the altered gene expression profiles and signal transduction pathways in host cells in response to the majority of human/animal RNA viruses opens new directions for basic and clinical research on viral pathogenesis, and also provides valuable biomarkers for researchers to select gene targets in the development of diagnostic tests and antiviral therapeutics for a number of infectious diseases.
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  Data: <searchLink fieldCode="AR" term="%22Decheng+Yang%22">Decheng Yang</searchLink>
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  Data: eBook.
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  Data: <searchLink fieldCode="DE" term="%22RNA+interference%22">RNA interference</searchLink><br /><searchLink fieldCode="DE" term="%22RNA+viruses%22">RNA viruses</searchLink><br /><searchLink fieldCode="DE" term="%22Viral+genetics%22">Viral genetics</searchLink>
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RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 579.25
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: RNA interference
        Type: general
      – SubjectFull: RNA viruses
        Type: general
      – SubjectFull: Viral genetics
        Type: general
    Titles:
      – TitleFull: Rna Viruses: Host Gene Responses To Infections
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Decheng Yang
      – PersonEntity:
          Name:
            NameFull: Decheng Yang
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2009
            – D: 04
              M: 02
              Type: profile
              Y: 2014
          Identifiers:
            – Type: isbn-print
              Value: 9789812833792
            – Type: isbn-electronic
              Value: 9789812833808
          Titles:
            – TitleFull: Rna Viruses: Host Gene Responses To Infections
              Type: main
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