Bibliographic Details
| Title: |
Hypothalamic-pituitary-adrenal (HPA) system activity in depression and infection with Borna disease virus and Chlamydia pneumoniae. |
| Authors: |
Deuschle, M, Bode, L, Schnitzler, P, Meyding-Lamade, U, Plesch, A, Ludwig, H, Hamann, B, Heuser, I |
| Source: |
Molecular Psychiatry. 2003, Vol. 8 Issue 5, p469. 2p. |
| Subjects: |
Hypothalamic-pituitary-adrenal axis, Immunology, Borna disease virus, Chlamydophila pneumoniae |
| Abstract: |
The article studies the association of severe depression with mutual immune and hypothala-mic-pituitary-adrenal (HPA) system activation. Based on a normative database, morning saliva concentrations above 25 nmol/l are indicative of HPA system activation. Relationship of HPA system activity with impaired immune functions promote borna disease virus (BDV) replication. In contrast to active BDV infection, chlamydia pneumoniae sero-positive patients did not show increased baseline HPA system activity. |
| Database: |
Psychology and Behavioral Sciences Collection |
