View in EDS HTML Full Text PDF Full Text

The Framingham cardiovascular risk score in multiple sclerosis.

Saved in:
Bibliographic Details
Title: The Framingham cardiovascular risk score in multiple sclerosis.
Authors: Moccia, M., Lanzillo, R., Palladino, R., Maniscalco, G. T., De Rosa, A., Russo, C., Massarelli, M., Carotenuto, A., Postiglione, E., Caporale, O., Triassi, M., Brescia Morra, V.
Source: European Journal of Neurology. Aug2015, Vol. 22 Issue 8, p1176-1183. 8p. 2 Charts, 2 Graphs.
Subjects: Multiple sclerosis diagnosis, Multiple sclerosis treatment, Patients, Cardiovascular diseases, Cardiovascular diseases risk factors, Neurology
Abstract: Background and purpose Cardiovascular risk factors can increase the risk of multiple sclerosis ( MS) and modify its course. However, such factors possibly interact, determining a global cardiovascular risk. Our aim was to compare the global cardiovascular risk of subjects with and without MS with the simplified 10-year Framingham General Cardiovascular Disease Risk Score ( FR) and to evaluate its importance on MS-related outcomes. Methods Age, gender, smoking status, body mass index, systolic blood pressure, type II diabetes and use of antihypertensive medications were recorded in subjects with and without MS to estimate the FR, an individualized percentage risk score estimating the 10-year likelihood of cardiovascular events. Results In total, 265 MS subjects were identified with 530 matched controls. A t test showed similar FR in cases and controls ( P = 0.212). Secondary progressive MS presented significantly higher FR compared to relapsing−remitting MS ( P < 0.001). Linear regression analysis showed a direct relationship between FR and Expanded Disability Status Scale ( P < 0.001) and MS Severity Scale ( P < 0.001). Conclusion The FR, evaluating the global cardiovascular health by the interaction amongst different risk factors, relates to MS disability, severity and course. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 103668432
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The Framingham cardiovascular risk score in multiple sclerosis.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Moccia%2C+M%2E%22&quot;&gt;Moccia, M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lanzillo%2C+R%2E%22&quot;&gt;Lanzillo, R.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Palladino%2C+R%2E%22&quot;&gt;Palladino, R.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Maniscalco%2C+G%2E+T%2E%22&quot;&gt;Maniscalco, G. T.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22De+Rosa%2C+A%2E%22&quot;&gt;De Rosa, A.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Russo%2C+C%2E%22&quot;&gt;Russo, C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Massarelli%2C+M%2E%22&quot;&gt;Massarelli, M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Carotenuto%2C+A%2E%22&quot;&gt;Carotenuto, A.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Postiglione%2C+E%2E%22&quot;&gt;Postiglione, E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Caporale%2C+O%2E%22&quot;&gt;Caporale, O.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Triassi%2C+M%2E%22&quot;&gt;Triassi, M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Brescia+Morra%2C+V%2E%22&quot;&gt;Brescia Morra, V.&lt;/searchLink&gt;
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Journal+of+Neurology%22&quot;&gt;European Journal of Neurology&lt;/searchLink&gt;. Aug2015, Vol. 22 Issue 8, p1176-1183. 8p. 2 Charts, 2 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Multiple+sclerosis+diagnosis%22&quot;&gt;Multiple sclerosis diagnosis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Multiple+sclerosis+treatment%22&quot;&gt;Multiple sclerosis treatment&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Patients%22&quot;&gt;Patients&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cardiovascular+diseases%22&quot;&gt;Cardiovascular diseases&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cardiovascular+diseases+risk+factors%22&quot;&gt;Cardiovascular diseases risk factors&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Neurology%22&quot;&gt;Neurology&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background and purpose Cardiovascular risk factors can increase the risk of multiple sclerosis ( MS) and modify its course. However, such factors possibly interact, determining a global cardiovascular risk. Our aim was to compare the global cardiovascular risk of subjects with and without MS with the simplified 10-year Framingham General Cardiovascular Disease Risk Score ( FR) and to evaluate its importance on MS-related outcomes. Methods Age, gender, smoking status, body mass index, systolic blood pressure, type II diabetes and use of antihypertensive medications were recorded in subjects with and without MS to estimate the FR, an individualized percentage risk score estimating the 10-year likelihood of cardiovascular events. Results In total, 265 MS subjects were identified with 530 matched controls. A t test showed similar FR in cases and controls ( P = 0.212). Secondary progressive MS presented significantly higher FR compared to relapsing−remitting MS ( P &lt; 0.001). Linear regression analysis showed a direct relationship between FR and Expanded Disability Status Scale ( P &lt; 0.001) and MS Severity Scale ( P &lt; 0.001). Conclusion The FR, evaluating the global cardiovascular health by the interaction amongst different risk factors, relates to MS disability, severity and course. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=103668432
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/ene.12720
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 1176
    Subjects:
      – SubjectFull: Multiple sclerosis diagnosis
        Type: general
      – SubjectFull: Multiple sclerosis treatment
        Type: general
      – SubjectFull: Patients
        Type: general
      – SubjectFull: Cardiovascular diseases
        Type: general
      – SubjectFull: Cardiovascular diseases risk factors
        Type: general
      – SubjectFull: Neurology
        Type: general
    Titles:
      – TitleFull: The Framingham cardiovascular risk score in multiple sclerosis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Moccia, M.
      – PersonEntity:
          Name:
            NameFull: Lanzillo, R.
      – PersonEntity:
          Name:
            NameFull: Palladino, R.
      – PersonEntity:
          Name:
            NameFull: Maniscalco, G. T.
      – PersonEntity:
          Name:
            NameFull: De Rosa, A.
      – PersonEntity:
          Name:
            NameFull: Russo, C.
      – PersonEntity:
          Name:
            NameFull: Massarelli, M.
      – PersonEntity:
          Name:
            NameFull: Carotenuto, A.
      – PersonEntity:
          Name:
            NameFull: Postiglione, E.
      – PersonEntity:
          Name:
            NameFull: Caporale, O.
      – PersonEntity:
          Name:
            NameFull: Triassi, M.
      – PersonEntity:
          Name:
            NameFull: Brescia Morra, V.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 08
              Text: Aug2015
              Type: published
              Y: 2015
          Identifiers:
            – Type: issn-print
              Value: 13515101
          Numbering:
            – Type: volume
              Value: 22
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: European Journal of Neurology
              Type: main
ResultId 1