Immunocytological test to detect adult carriers of (--SEA/) deletional alpha-thalassaemia.
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| Title: | Immunocytological test to detect adult carriers of (--SEA/) deletional alpha-thalassaemia. |
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| Authors: | Tang, Wozhan, Luo, Hong-Yuan, Eng, Barry, Waye, John S, Chui, David H K, Tang, W (AUTHOR), Luo, H Y (AUTHOR), Eng, B (AUTHOR), Waye, J S (AUTHOR), Chui, D H (AUTHOR) |
| Source: | Lancet. 11/6/1993, Vol. 342 Issue 8880, p1145-1147. 3p. |
| Abstract: | The gene frequency for (--SEA/) deletional alpha-thalassaemia is high in Southeast Asian populations. We report a simple immunocytological test that is highly sensitive and specific for the detection of adult carriers of the (--SEA/) deletion. We prospectively studied 206 consecutive adult blood samples. All 41 with the (--SEA/) deletion had a positive test; all but 1 of the 165 non-carriers were negative. This test, whose major requirement is a fluorescence microscope, should be useful to identify couples at risk of conceiving fetuses with homozygous alpha-thalassaemia. [ABSTRACT FROM AUTHOR] |
| Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| FullText | Text: Availability: 1 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 105851558 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Immunocytological test to detect adult carriers of (--SEA/) deletional alpha-thalassaemia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Tang%2C+Wozhan%22">Tang, Wozhan</searchLink><br /><searchLink fieldCode="AR" term="%22Luo%2C+Hong-Yuan%22">Luo, Hong-Yuan</searchLink><br /><searchLink fieldCode="AR" term="%22Eng%2C+Barry%22">Eng, Barry</searchLink><br /><searchLink fieldCode="AR" term="%22Waye%2C+John+S%22">Waye, John S</searchLink><br /><searchLink fieldCode="AR" term="%22Chui%2C+David+H+K%22">Chui, David H K</searchLink><br /><searchLink fieldCode="AR" term="%22Tang%2C+W%22">Tang, W</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Luo%2C+H+Y%22">Luo, H Y</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Eng%2C+B%22">Eng, B</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Waye%2C+J+S%22">Waye, J S</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chui%2C+D+H%22">Chui, D H</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 11/6/1993, Vol. 342 Issue 8880, p1145-1147. 3p. – Name: Abstract Label: Abstract Group: Ab Data: The gene frequency for (--SEA/) deletional alpha-thalassaemia is high in Southeast Asian populations. We report a simple immunocytological test that is highly sensitive and specific for the detection of adult carriers of the (--SEA/) deletion. We prospectively studied 206 consecutive adult blood samples. All 41 with the (--SEA/) deletion had a positive test; all but 1 of the 165 non-carriers were negative. This test, whose major requirement is a fluorescence microscope, should be useful to identify couples at risk of conceiving fetuses with homozygous alpha-thalassaemia. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=105851558 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/0140-6736(93)92125-d Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 3 StartPage: 1145 Titles: – TitleFull: Immunocytological test to detect adult carriers of (--SEA/) deletional alpha-thalassaemia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tang, Wozhan – PersonEntity: Name: NameFull: Luo, Hong-Yuan – PersonEntity: Name: NameFull: Eng, Barry – PersonEntity: Name: NameFull: Waye, John S – PersonEntity: Name: NameFull: Chui, David H K – PersonEntity: Name: NameFull: Tang, W – PersonEntity: Name: NameFull: Luo, H Y – PersonEntity: Name: NameFull: Eng, B – PersonEntity: Name: NameFull: Waye, J S – PersonEntity: Name: NameFull: Chui, D H IsPartOfRelationships: – BibEntity: Dates: – D: 06 M: 11 Text: 11/6/1993 Type: published Y: 1993 Identifiers: – Type: issn-print Value: 01406736 Numbering: – Type: volume Value: 342 – Type: issue Value: 8880 Titles: – TitleFull: Lancet Type: main |
| ResultId | 1 |
