Bibliographic Details
| Title: |
Pneumocystis jiroveci infection in patients with hyper-immunoglobulin E syndrome. |
| Authors: |
Freeman AF (AUTHOR), Davis J (AUTHOR), Anderson VL (AUTHOR), Barson W (AUTHOR), Darnell DN (AUTHOR), Puck JM (AUTHOR), Holland SM (AUTHOR) |
| Source: |
Pediatrics. Oct2006, Vol. 118 Issue 4, pe1271-5. 1p. |
| Abstract: |
The hyper-immunoglobulin E syndrome is a primary immunodeficiency characterized by recurrent pyogenic skin and lung abscesses, dermatitis, and elevated serum immunoglobulin E levels. Pneumocystis jiroveci (formerly Pneumocystis carinii) is not typically associated with hyper-immunoglobulin E syndrome. We identified 7 patients with hyper-immunoglobulin E syndrome with P. jiroveci detected in respiratory or pulmonary pathology specimens. In 5 patients it was the sole pathogen, and in 2 other patients it contributed to a polymicrobial etiology. No consistent prophylaxis was given, and there have been no recurrences on long-term follow-up. Our experience suggests that P. jiroveci can cause pneumonia in patients with hyper-immunoglobulin E syndrome both with and without chronic lung disease. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
