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Pneumocystis jiroveci infection in patients with hyper-immunoglobulin E syndrome.

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Title: Pneumocystis jiroveci infection in patients with hyper-immunoglobulin E syndrome.
Authors: Freeman AF (AUTHOR), Davis J (AUTHOR), Anderson VL (AUTHOR), Barson W (AUTHOR), Darnell DN (AUTHOR), Puck JM (AUTHOR), Holland SM (AUTHOR)
Source: Pediatrics. Oct2006, Vol. 118 Issue 4, pe1271-5. 1p.
Abstract: The hyper-immunoglobulin E syndrome is a primary immunodeficiency characterized by recurrent pyogenic skin and lung abscesses, dermatitis, and elevated serum immunoglobulin E levels. Pneumocystis jiroveci (formerly Pneumocystis carinii) is not typically associated with hyper-immunoglobulin E syndrome. We identified 7 patients with hyper-immunoglobulin E syndrome with P. jiroveci detected in respiratory or pulmonary pathology specimens. In 5 patients it was the sole pathogen, and in 2 other patients it contributed to a polymicrobial etiology. No consistent prophylaxis was given, and there have been no recurrences on long-term follow-up. Our experience suggests that P. jiroveci can cause pneumonia in patients with hyper-immunoglobulin E syndrome both with and without chronic lung disease. [ABSTRACT FROM AUTHOR]
Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Pneumocystis jiroveci infection in patients with hyper-immunoglobulin E syndrome.
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  Data: <searchLink fieldCode="AR" term="%22Freeman+AF%22">Freeman AF</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Davis+J%22">Davis J</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Anderson+VL%22">Anderson VL</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Barson+W%22">Barson W</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Darnell+DN%22">Darnell DN</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Puck+JM%22">Puck JM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Holland+SM%22">Holland SM</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. Oct2006, Vol. 118 Issue 4, pe1271-5. 1p.
– Name: Abstract
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  Data: The hyper-immunoglobulin E syndrome is a primary immunodeficiency characterized by recurrent pyogenic skin and lung abscesses, dermatitis, and elevated serum immunoglobulin E levels. Pneumocystis jiroveci (formerly Pneumocystis carinii) is not typically associated with hyper-immunoglobulin E syndrome. We identified 7 patients with hyper-immunoglobulin E syndrome with P. jiroveci detected in respiratory or pulmonary pathology specimens. In 5 patients it was the sole pathogen, and in 2 other patients it contributed to a polymicrobial etiology. No consistent prophylaxis was given, and there have been no recurrences on long-term follow-up. Our experience suggests that P. jiroveci can cause pneumonia in patients with hyper-immunoglobulin E syndrome both with and without chronic lung disease. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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