View in EDS

Blood pressure at 6 years of age after prenatal exposure to betamethasone: follow-up results of a randomized, controlled trial.

Saved in:
Bibliographic Details
Title: Blood pressure at 6 years of age after prenatal exposure to betamethasone: follow-up results of a randomized, controlled trial.
Authors: Dalziel SR (AUTHOR), Liang A (AUTHOR), Parag V (AUTHOR), Rodgers A (AUTHOR), Harding JE (AUTHOR)
Source: Pediatrics. 2004 Sep Supplement, Vol. 114 Issue 3, pe373-7. 1p.
Abstract: OBJECTIVE: To determine whether prenatal exposure to betamethasone for the prevention of neonatal respiratory distress syndrome (RDS) alters blood pressure in childhood. DESIGN: Prospective follow-up study of a randomized, double-blind, placebo-controlled trial. SETTING: National Women's Hospital (Auckland, New Zealand). PARTICIPANTS: Two hundred twenty-three 6-year-old children of mothers who presented with unplanned premature labor and took part in a randomized, controlled trial of prenatal betamethasone therapy for the prevention of neonatal RDS. INTERVENTION: Mothers received 2 doses of betamethasone (12 mg) or placebo, administered through intramuscular injection, 24 hours apart. MAIN OUTCOME MEASURES: Systolic and diastolic blood pressure at 6 years of age. RESULTS: Children exposed prenatally to betamethasone (n = 121) did not differ in systolic or diastolic blood pressure from children exposed to placebo (n = 102) (mean difference: systolic: -1.6 mm Hg; 95% confidence interval: -4.1 to 0.8 mm Hg; diastolic: -0.3 mm Hg; 95% confidence interval: -2.5 to 1.8 mm Hg). CONCLUSION: Prenatal exposure to betamethasone for prevention of neonatal RDS does not alter blood pressure at 6 years of age. [ABSTRACT FROM AUTHOR]
Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 106632316
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Blood pressure at 6 years of age after prenatal exposure to betamethasone: follow-up results of a randomized, controlled trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Dalziel+SR%22">Dalziel SR</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liang+A%22">Liang A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Parag+V%22">Parag V</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rodgers+A%22">Rodgers A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Harding+JE%22">Harding JE</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. 2004 Sep Supplement, Vol. 114 Issue 3, pe373-7. 1p.
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: OBJECTIVE: To determine whether prenatal exposure to betamethasone for the prevention of neonatal respiratory distress syndrome (RDS) alters blood pressure in childhood. DESIGN: Prospective follow-up study of a randomized, double-blind, placebo-controlled trial. SETTING: National Women's Hospital (Auckland, New Zealand). PARTICIPANTS: Two hundred twenty-three 6-year-old children of mothers who presented with unplanned premature labor and took part in a randomized, controlled trial of prenatal betamethasone therapy for the prevention of neonatal RDS. INTERVENTION: Mothers received 2 doses of betamethasone (12 mg) or placebo, administered through intramuscular injection, 24 hours apart. MAIN OUTCOME MEASURES: Systolic and diastolic blood pressure at 6 years of age. RESULTS: Children exposed prenatally to betamethasone (n = 121) did not differ in systolic or diastolic blood pressure from children exposed to placebo (n = 102) (mean difference: systolic: -1.6 mm Hg; 95% confidence interval: -4.1 to 0.8 mm Hg; diastolic: -0.3 mm Hg; 95% confidence interval: -2.5 to 1.8 mm Hg). CONCLUSION: Prenatal exposure to betamethasone for prevention of neonatal RDS does not alter blood pressure at 6 years of age. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=106632316
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1542/peds.2004-0196
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: e373
    Titles:
      – TitleFull: Blood pressure at 6 years of age after prenatal exposure to betamethasone: follow-up results of a randomized, controlled trial.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Dalziel SR
      – PersonEntity:
          Name:
            NameFull: Liang A
      – PersonEntity:
          Name:
            NameFull: Parag V
      – PersonEntity:
          Name:
            NameFull: Rodgers A
      – PersonEntity:
          Name:
            NameFull: Harding JE
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 09
              Text: 2004 Sep Supplement
              Type: published
              Y: 2004
          Identifiers:
            – Type: issn-print
              Value: 00314005
          Numbering:
            – Type: volume
              Value: 114
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Pediatrics
              Type: main
ResultId 1