Natural outcome of cannabis use disorder: a 3-year longitudinal follow-up.

Saved in:

Bibliographic Details
Title:	Natural outcome of cannabis use disorder: a 3-year longitudinal follow-up.
Authors:	Feingold, Daniel, Fox, Jonah, Rehm, Jürgen, Lev‐Ran, Shaul
Source:	Addiction. Dec2015, Vol. 110 Issue 12, p1963-1974. 12p. 4 Charts.
Subjects:	Disease remission, Drug addiction, Substance abuse relapse, Diagnosis, Cannabis (Genus)
Geographic Terms:	United States
Abstract:	Aims To assess the prevalence and correlates of remission from cannabis use disorders (CUDs), focusing on the proportion of individuals with CUDs that remit without abstaining from cannabis use. Design Three-year longitudinal study. Setting Wave 1 (2001) and wave 2 (2004) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a nationally representative sample of US adults aged 18 years and over. Participants Our sample included 444 individuals diagnosed with DSM-IV cannabis abuse and/or dependence during the 12 months prior to wave 1 of the NESARC. Measurements Baseline socio-demographic and clinical correlates were analysed for possible outcomes of CUDs after 3 years: abstinent remission, non-abstinent remission and sustained disorder. Findings Approximately two-thirds (67%) of individuals with baseline CUD remitted at follow-up. Approximately 37% of those who remitted were non-abstinent. Remission was associated with Hispanic ethnicity [odds ratio (OR) = 2.59; 95% confidence interval (CI) = 1.27-4.87], baseline daily or almost daily use of cannabis (OR = 1.91; 95% CI = 1.15-3.16), baseline use of other drugs (OR = 1.63; 95% CI = 1.04-2.56) and two or more medical conditions at baseline (OR = 8.40; 95% CI = 2.67-26.41). Non-abstinent remission was associated with baseline daily or almost daily use of cannabis (OR = 1.92; 95% CI = 1.05-3.51). Conclusions A substantial level of remission from cannabis use disorders (CUDs), including non-abstinent remission, suggests that the nature of CUDs may be more unstable than reported previously. [ABSTRACT FROM AUTHOR]
	Copyright of Addiction is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database:	Psychology and Behavioral Sciences Collection

Description
Abstract:	Aims To assess the prevalence and correlates of remission from cannabis use disorders (CUDs), focusing on the proportion of individuals with CUDs that remit without abstaining from cannabis use. Design Three-year longitudinal study. Setting Wave 1 (2001) and wave 2 (2004) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a nationally representative sample of US adults aged 18 years and over. Participants Our sample included 444 individuals diagnosed with DSM-IV cannabis abuse and/or dependence during the 12 months prior to wave 1 of the NESARC. Measurements Baseline socio-demographic and clinical correlates were analysed for possible outcomes of CUDs after 3 years: abstinent remission, non-abstinent remission and sustained disorder. Findings Approximately two-thirds (67%) of individuals with baseline CUD remitted at follow-up. Approximately 37% of those who remitted were non-abstinent. Remission was associated with Hispanic ethnicity [odds ratio (OR) = 2.59; 95% confidence interval (CI) = 1.27-4.87], baseline daily or almost daily use of cannabis (OR = 1.91; 95% CI = 1.15-3.16), baseline use of other drugs (OR = 1.63; 95% CI = 1.04-2.56) and two or more medical conditions at baseline (OR = 8.40; 95% CI = 2.67-26.41). Non-abstinent remission was associated with baseline daily or almost daily use of cannabis (OR = 1.92; 95% CI = 1.05-3.51). Conclusions A substantial level of remission from cannabis use disorders (CUDs), including non-abstinent remission, suggests that the nature of CUDs may be more unstable than reported previously. [ABSTRACT FROM AUTHOR]
ISSN:	09652140
DOI:	10.1111/add.13071