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Metabolic syndrome in first-time hospitalized patients with depression: a 1-year follow-up study.

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Title: Metabolic syndrome in first-time hospitalized patients with depression: a 1-year follow-up study.
Authors: Nyboe, L., Vestergaard, C. H., Lund, H., Møller, M. K., Videbech, P.
Source: Acta Psychiatrica Scandinavica. Mar2016, Vol. 133 Issue 3, p241-248. 8p. 5 Charts.
Subjects: Depressed persons, Metabolic syndrome, Metabolic syndrome risk factors, Antipsychotic agents, Hospital patients, Physiological aspects of physical fitness, Disease prevalence, Diseases, Patients
Abstract: Objective Studies on metabolic syndrome (MetS) in younger patients with depression are few. We examined the prevalence and progression of MetS in first-time hospitalized patients with depression during 1 year of follow-up. Furthermore, we explored putative risk factors of MetS. Method We evaluated MetS and its components in first-time hospitalized patients with depression ( N = 52) and healthy controls ( N = 50) (18-45 years). Physical activity, aerobic fitness, sleeping disturbances, smoking and dietary habits, and psychopharmacological treatment were recorded at baseline for all participants and after 1 year for the patients. Results Patients had significantly higher waist circumference ( WC) and lower high-density lipoproteins compared with healthy controls ( P < 0.05). Patients had higher prevalence of MetS, but this was not significant when adjusted for age. Patients had significant increase in WC and triglycerides and a non-significant increase in the prevalence of MetS. Antipsychotic medication ( OR 10.5, 95% CI 1.18-94.14) and low aerobic fitness ( OR 0.79, 95% CI 0.68-0.93) were significantly correlated with MetS ( P < 0.05). Conclusion Metabolic syndrome is highly prevalent in younger, severely depressed patients and the incidence increases during 1 year of follow-up. Low aerobic fitness and use of atypical antipsychotics are strongly correlated with MetS. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Metabolic syndrome in first-time hospitalized patients with depression: a 1-year follow-up study.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Acta+Psychiatrica+Scandinavica%22&quot;&gt;Acta Psychiatrica Scandinavica&lt;/searchLink&gt;. Mar2016, Vol. 133 Issue 3, p241-248. 8p. 5 Charts.
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  Data: Objective Studies on metabolic syndrome (MetS) in younger patients with depression are few. We examined the prevalence and progression of MetS in first-time hospitalized patients with depression during 1 year of follow-up. Furthermore, we explored putative risk factors of MetS. Method We evaluated MetS and its components in first-time hospitalized patients with depression ( N = 52) and healthy controls ( N = 50) (18-45 years). Physical activity, aerobic fitness, sleeping disturbances, smoking and dietary habits, and psychopharmacological treatment were recorded at baseline for all participants and after 1 year for the patients. Results Patients had significantly higher waist circumference ( WC) and lower high-density lipoproteins compared with healthy controls ( P &lt; 0.05). Patients had higher prevalence of MetS, but this was not significant when adjusted for age. Patients had significant increase in WC and triglycerides and a non-significant increase in the prevalence of MetS. Antipsychotic medication ( OR 10.5, 95% CI 1.18-94.14) and low aerobic fitness ( OR 0.79, 95% CI 0.68-0.93) were significantly correlated with MetS ( P &lt; 0.05). Conclusion Metabolic syndrome is highly prevalent in younger, severely depressed patients and the incidence increases during 1 year of follow-up. Low aerobic fitness and use of atypical antipsychotics are strongly correlated with MetS. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1111/acps.12470
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        Text: English
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        Type: general
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              Text: Mar2016
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