Clinical high risk for psychosis: the association between momentary stress, affective and psychotic symptoms.
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| Title: | Clinical high risk for psychosis: the association between momentary stress, affective and psychotic symptoms. |
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| Authors: | Steen, Y., Gimpel‐Drees, J., Lataster, T., Viechtbauer, W., Simons, C. J. P., Lardinois, M., Michel, T. M., Janssen, B., Bechdolf, A., Wagner, M., Myin‐Germeys, I. |
| Source: | Acta Psychiatrica Scandinavica. Jul2017, Vol. 136 Issue 1, p63-73. 11p. 3 Charts, 1 Graph. |
| Subjects: | Psychoses, Risk-taking behavior, Probability theory, Stress management, Disability evaluation |
| Abstract: | Objective The aim of this study was to assess associations between momentary stress and both affective and psychotic symptoms in everyday life of individuals at clinical high risk ( CHR), compared to chronic psychotic patients and healthy controls, in search for evidence of early stress sensitization. It also assessed whether psychotic experiences were experienced as stressful. Method The experience sampling method was used to measure affective and psychotic reactivity to everyday stressful activities, events and social situations in 22 CHR patients, 24 patients with a psychotic disorder and 26 healthy controls. Results Multilevel models showed significantly larger associations between negative affect ( NA) and activity-related stress for CHR patients than for psychotic patients ( P = 0.008) and for CHR compared to controls ( P < 0.001). Similarly, the association between activity-related stress and psychotic symptoms was larger in CHR than in patients ( P = 0.02). Finally, the association between NA and symptoms ( P < 0.001) was larger in CHR than in patients. Conclusion Stress sensitization seems to play a role particularly in the early phase of psychosis development as results suggest that CHR patients are more sensitive to daily life stressors than psychotic patients. In this early phase, psychotic experiences also contributed to the experience of stress. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Objective The aim of this study was to assess associations between momentary stress and both affective and psychotic symptoms in everyday life of individuals at clinical high risk ( CHR), compared to chronic psychotic patients and healthy controls, in search for evidence of early stress sensitization. It also assessed whether psychotic experiences were experienced as stressful. Method The experience sampling method was used to measure affective and psychotic reactivity to everyday stressful activities, events and social situations in 22 CHR patients, 24 patients with a psychotic disorder and 26 healthy controls. Results Multilevel models showed significantly larger associations between negative affect ( NA) and activity-related stress for CHR patients than for psychotic patients ( P = 0.008) and for CHR compared to controls ( P < 0.001). Similarly, the association between activity-related stress and psychotic symptoms was larger in CHR than in patients ( P = 0.02). Finally, the association between NA and symptoms ( P < 0.001) was larger in CHR than in patients. Conclusion Stress sensitization seems to play a role particularly in the early phase of psychosis development as results suggest that CHR patients are more sensitive to daily life stressors than psychotic patients. In this early phase, psychotic experiences also contributed to the experience of stress. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 0001690X |
| DOI: | 10.1111/acps.12714 |
