Bibliographic Details
| Title: |
Plasma Fluphenazine Concentrations in Outpatients Receiving Fluphenazine Decanoate (Modecate). |
| Authors: |
Kimber, Nigel M., Marriott, Peter F., Norman, Trevor R., Burrows, Graham D. |
| Source: |
Human Psychopharmacology: Clinical & Experimental. Dec86, Vol. 1 Issue 2, p89-92. 4p. |
| Subjects: |
Psychiatric drugs, Patients, Analytical biochemistry, Extrapyramidal disorders, Tardive dyskinesia, Movement disorders |
| Abstract: |
Plasma fluphenazine concentrations were measured by neuroleptic radioreceptor assay in 17 outpatients receiving chronic treatment with intramuscular fluphenazine decanoate. The range of concentrations was 05-24 μg/L over the dosage range of 0.30-3.2 mg/d. Age, sex and smoking status had no influence on plasma fluphenazine concentrations, which were not correlated with dose (expressed as mg/kg/d). There was no significant correlation between plasma concentration and clinical status of the patients. No difference in plasma concentration between patients with extrapyramidal signs or tardive dyskinesia and those without signs were observed. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
