Plasma Fluphenazine Concentrations in Outpatients Receiving Fluphenazine Decanoate (Modecate).
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| Title: | Plasma Fluphenazine Concentrations in Outpatients Receiving Fluphenazine Decanoate (Modecate). |
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| Authors: | Kimber, Nigel M., Marriott, Peter F., Norman, Trevor R., Burrows, Graham D. |
| Source: | Human Psychopharmacology: Clinical & Experimental. Dec86, Vol. 1 Issue 2, p89-92. 4p. |
| Subjects: | Psychiatric drugs, Patients, Analytical biochemistry, Extrapyramidal disorders, Tardive dyskinesia, Movement disorders |
| Abstract: | Plasma fluphenazine concentrations were measured by neuroleptic radioreceptor assay in 17 outpatients receiving chronic treatment with intramuscular fluphenazine decanoate. The range of concentrations was 05-24 μg/L over the dosage range of 0.30-3.2 mg/d. Age, sex and smoking status had no influence on plasma fluphenazine concentrations, which were not correlated with dose (expressed as mg/kg/d). There was no significant correlation between plasma concentration and clinical status of the patients. No difference in plasma concentration between patients with extrapyramidal signs or tardive dyskinesia and those without signs were observed. [ABSTRACT FROM AUTHOR] |
| Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 12363493 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Plasma Fluphenazine Concentrations in Outpatients Receiving Fluphenazine Decanoate (Modecate). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Kimber%2C+Nigel+M%2E%22">Kimber, Nigel M.</searchLink><br /><searchLink fieldCode="AR" term="%22Marriott%2C+Peter+F%2E%22">Marriott, Peter F.</searchLink><br /><searchLink fieldCode="AR" term="%22Norman%2C+Trevor+R%2E%22">Norman, Trevor R.</searchLink><br /><searchLink fieldCode="AR" term="%22Burrows%2C+Graham+D%2E%22">Burrows, Graham D.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Human+Psychopharmacology%3A+Clinical+%26+Experimental%22">Human Psychopharmacology: Clinical & Experimental</searchLink>. Dec86, Vol. 1 Issue 2, p89-92. 4p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Psychiatric+drugs%22">Psychiatric drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink><br /><searchLink fieldCode="DE" term="%22Analytical+biochemistry%22">Analytical biochemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Extrapyramidal+disorders%22">Extrapyramidal disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Tardive+dyskinesia%22">Tardive dyskinesia</searchLink><br /><searchLink fieldCode="DE" term="%22Movement+disorders%22">Movement disorders</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Plasma fluphenazine concentrations were measured by neuroleptic radioreceptor assay in 17 outpatients receiving chronic treatment with intramuscular fluphenazine decanoate. The range of concentrations was 05-24 μg/L over the dosage range of 0.30-3.2 mg/d. Age, sex and smoking status had no influence on plasma fluphenazine concentrations, which were not correlated with dose (expressed as mg/kg/d). There was no significant correlation between plasma concentration and clinical status of the patients. No difference in plasma concentration between patients with extrapyramidal signs or tardive dyskinesia and those without signs were observed. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/hup.470010205 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 4 StartPage: 89 Subjects: – SubjectFull: Psychiatric drugs Type: general – SubjectFull: Patients Type: general – SubjectFull: Analytical biochemistry Type: general – SubjectFull: Extrapyramidal disorders Type: general – SubjectFull: Tardive dyskinesia Type: general – SubjectFull: Movement disorders Type: general Titles: – TitleFull: Plasma Fluphenazine Concentrations in Outpatients Receiving Fluphenazine Decanoate (Modecate). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kimber, Nigel M. – PersonEntity: Name: NameFull: Marriott, Peter F. – PersonEntity: Name: NameFull: Norman, Trevor R. – PersonEntity: Name: NameFull: Burrows, Graham D. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec86 Type: published Y: 1986 Identifiers: – Type: issn-print Value: 08856222 Numbering: – Type: volume Value: 1 – Type: issue Value: 2 Titles: – TitleFull: Human Psychopharmacology: Clinical & Experimental Type: main |
| ResultId | 1 |
