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The central cannabinoid receptor type-2 (CB2) and chronic pain.

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Title: The central cannabinoid receptor type-2 (CB2) and chronic pain.
Authors: Shang, Yuchao (AUTHOR), Tang, Yuying (AUTHOR)
Source: International Journal of Neuroscience. Sep2017, Vol. 127 Issue 9, p812-823. 12p.
Subjects: Cannabinoid receptors, Chronic pain, Analgesia, Cytokines, Drug side effects
Abstract: Cannabinoid receptor type-2 (CB2, CB2 receptor or CB2-R) mediates analgesia via two mechanisms. CB2 receptors contained in peripheral immune tissue mediate analgesia by altering cytokine profiles, and thus have little adverse effects on central nervous systems (CNSs). CB2 is also expressed in the neurons and glial cells of the CNS. This neuronal expression may also contribute to pain attenuation. The CB2 receptor has been proposed as a potential target in treating chronic pain of several etiologies. [ABSTRACT FROM PUBLISHER]
Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 123952796
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: The central cannabinoid receptor type-2 (CB2) and chronic pain.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Shang%2C+Yuchao%22">Shang, Yuchao</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tang%2C+Yuying%22">Tang, Yuying</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Neuroscience%22">International Journal of Neuroscience</searchLink>. Sep2017, Vol. 127 Issue 9, p812-823. 12p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Cannabinoid+receptors%22">Cannabinoid receptors</searchLink><br /><searchLink fieldCode="DE" term="%22Chronic+pain%22">Chronic pain</searchLink><br /><searchLink fieldCode="DE" term="%22Analgesia%22">Analgesia</searchLink><br /><searchLink fieldCode="DE" term="%22Cytokines%22">Cytokines</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+side+effects%22">Drug side effects</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Cannabinoid receptor type-2 (CB2, CB2 receptor or CB2-R) mediates analgesia via two mechanisms. CB2 receptors contained in peripheral immune tissue mediate analgesia by altering cytokine profiles, and thus have little adverse effects on central nervous systems (CNSs). CB2 is also expressed in the neurons and glial cells of the CNS. This neuronal expression may also contribute to pain attenuation. The CB2 receptor has been proposed as a potential target in treating chronic pain of several etiologies. [ABSTRACT FROM PUBLISHER]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=123952796
RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1080/00207454.2016.1257992
    Languages:
      – Code: eng
        Text: English
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        PageCount: 12
        StartPage: 812
    Subjects:
      – SubjectFull: Cannabinoid receptors
        Type: general
      – SubjectFull: Chronic pain
        Type: general
      – SubjectFull: Analgesia
        Type: general
      – SubjectFull: Cytokines
        Type: general
      – SubjectFull: Drug side effects
        Type: general
    Titles:
      – TitleFull: The central cannabinoid receptor type-2 (CB2) and chronic pain.
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            NameFull: Shang, Yuchao
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            NameFull: Tang, Yuying
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              M: 09
              Text: Sep2017
              Type: published
              Y: 2017
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              Value: 127
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            – TitleFull: International Journal of Neuroscience
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