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The relationships between brain structural changes and perceived loneliness in older adults suffering from late-life depression.

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Title: The relationships between brain structural changes and perceived loneliness in older adults suffering from late-life depression.
Authors: Sin, Emily L. L., Liu, Ho‐Ling, Lee, Shwu‐Hua, Huang, Chih‐Mao, Wai, Yau‐Yau, Chen, Yao‐Liang, Chan, Chetwyn C. H., Lin, Chemin, Lee, Tatia M. C., Liu, Ho-Ling (AUTHOR), Lee, Shwu-Hua (AUTHOR), Huang, Chih-Mao (AUTHOR), Wai, Yau-Yau (AUTHOR), Chen, Yao-Liang (AUTHOR)
Source: International Journal of Geriatric Psychiatry. Apr2018, Vol. 33 Issue 4, p606-612. 7p. 1 Chart, 2 Graphs.
Subjects: Depression in old age, Loneliness, Loneliness in old age, Health of older people, Health risk factors, Psychology, Brain anatomy, Mental depression, Comparative studies, Magnetic resonance imaging, Research methodology, Medical cooperation, Research, Reward (Psychology), Disease relapse, Evaluation research, Case-control method
Abstract: Objective: Late-life depression is a significant health risk factor for older adults, part of which is perceived loneliness. In this voxel-based morphometry study, we examined the relationships between perceived loneliness and depression recurrence.Methods: Fifty-two older adults were recruited, and they were split into 3 groups: single episode, multiple episodes, or normal control groups, according to their clinical histories.Results: This result suggests the level of functioning regarding the reward system may be negatively related to the number of depressive episodes. Taken together, the findings of this study offer important insight into the neural underpinnings of the course and chronicity of late-life depression. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
Description
Abstract:<bold>Objective: </bold>Late-life depression is a significant health risk factor for older adults, part of which is perceived loneliness. In this voxel-based morphometry study, we examined the relationships between perceived loneliness and depression recurrence.<bold>Methods: </bold>Fifty-two older adults were recruited, and they were split into 3 groups: single episode, multiple episodes, or normal control groups, according to their clinical histories.<bold>Results: </bold>This result suggests the level of functioning regarding the reward system may be negatively related to the number of depressive episodes. Taken together, the findings of this study offer important insight into the neural underpinnings of the course and chronicity of late-life depression. [ABSTRACT FROM AUTHOR]
ISSN:08856230
DOI:10.1002/gps.4831