Bibliographic Details
| Title: |
Routine terminations of pregnancy--should we screen for gestational trophoblastic neoplasia? |
| Authors: |
Seckl, Michael J., Gillmore, Roopinder, Foskett, Marianne, Sebire, Neil J., Rees, Helene, Newlands, Edward S. |
| Source: |
Lancet. 8/21/2004, Vol. 364 Issue 9435, p705-707. 3p. 2 Charts. |
| Subjects: |
Abortion, Trophoblastic tumors, Obstetrical research, Diagnosis of uterine diseases, Noninvasive diagnostic tests, Prognosis, Drug therapy, Medical screening, Pregnant women |
| Abstract: |
After termination of pregnancy for non-medical reasons, the products of conception are often not routinely examined for gestational trophoblastic neoplasia. Between 1995 and 2001 we identified 15 women without and 36 women with a pathological diagnosis of gestational trophoblastic neoplasia at the time of their pregnancy termination. Women without a diagnosis were significantly more likely to have subsequent life-threatening complications of gestational trophoblastic neoplasia (four of 15 vs none of 36; p=0.003), and to require surgical intervention (15 of 15 vs one of 36; p<0.0001) and chemotherapy (nine of 15 vs two of 36; p<0.0001). All women should be screened for gestational trophoblastic neoplasia after termination of pregnancy. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
