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Routine terminations of pregnancy--should we screen for gestational trophoblastic neoplasia?

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Title: Routine terminations of pregnancy--should we screen for gestational trophoblastic neoplasia?
Authors: Seckl, Michael J., Gillmore, Roopinder, Foskett, Marianne, Sebire, Neil J., Rees, Helene, Newlands, Edward S.
Source: Lancet. 8/21/2004, Vol. 364 Issue 9435, p705-707. 3p. 2 Charts.
Subjects: Abortion, Trophoblastic tumors, Obstetrical research, Diagnosis of uterine diseases, Noninvasive diagnostic tests, Prognosis, Drug therapy, Medical screening, Pregnant women
Abstract: After termination of pregnancy for non-medical reasons, the products of conception are often not routinely examined for gestational trophoblastic neoplasia. Between 1995 and 2001 we identified 15 women without and 36 women with a pathological diagnosis of gestational trophoblastic neoplasia at the time of their pregnancy termination. Women without a diagnosis were significantly more likely to have subsequent life-threatening complications of gestational trophoblastic neoplasia (four of 15 vs none of 36; p=0.003), and to require surgical intervention (15 of 15 vs one of 36; p<0.0001) and chemotherapy (nine of 15 vs two of 36; p<0.0001). All women should be screened for gestational trophoblastic neoplasia after termination of pregnancy. [ABSTRACT FROM AUTHOR]
Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: After termination of pregnancy for non-medical reasons, the products of conception are often not routinely examined for gestational trophoblastic neoplasia. Between 1995 and 2001 we identified 15 women without and 36 women with a pathological diagnosis of gestational trophoblastic neoplasia at the time of their pregnancy termination. Women without a diagnosis were significantly more likely to have subsequent life-threatening complications of gestational trophoblastic neoplasia (four of 15 vs none of 36; p=0.003), and to require surgical intervention (15 of 15 vs one of 36; p&lt;0.0001) and chemotherapy (nine of 15 vs two of 36; p&lt;0.0001). All women should be screened for gestational trophoblastic neoplasia after termination of pregnancy. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1016/S0140-6736(04)16898-0
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        Text: English
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    Subjects:
      – SubjectFull: Abortion
        Type: general
      – SubjectFull: Trophoblastic tumors
        Type: general
      – SubjectFull: Obstetrical research
        Type: general
      – SubjectFull: Diagnosis of uterine diseases
        Type: general
      – SubjectFull: Noninvasive diagnostic tests
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      – SubjectFull: Drug therapy
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      – SubjectFull: Medical screening
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      – SubjectFull: Pregnant women
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      – TitleFull: Routine terminations of pregnancy--should we screen for gestational trophoblastic neoplasia?
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              M: 08
              Text: 8/21/2004
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              Y: 2004
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