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Examining the Relationship between a Verbal Incidental Learning Measure from the WAIS-IV and Neuroimaging Biomarkers for Alzheimer's Pathology.

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Title: Examining the Relationship between a Verbal Incidental Learning Measure from the WAIS-IV and Neuroimaging Biomarkers for Alzheimer's Pathology.
Authors: Hammers, Dustin B. (AUTHOR), Kucera, Amanda (AUTHOR), Spencer, Robert J. (AUTHOR), Abildskov, Tracy J. (AUTHOR), Archibald, Zane G. (AUTHOR), Hoffman, John M. (AUTHOR), Wilde, Elizabeth A. (AUTHOR)
Source: Developmental Neuropsychology. Apr-Jun2020, Vol. 45 Issue 3, p95-109. 15p. 4 Charts, 2 Graphs.
Subjects: Incidental learning, Verbal learning, Neuropsychological tests, Wechsler Adult Intelligence Scale, Pathology, Brain imaging, Biomarkers
Abstract: Convergent validation of a verbal incidental learning (IL) task from the WAIS-IV using neuroimaging biomarkers is warranted to understand its sensitivity to Alzheimer's disease (AD) pathology. Fifty-five memory clinic patients aged 59 to 87 years received neuropsychological assessment, and measures of IL and quantitative brain imaging. Worse IL-Total Score and IL-Similarities performances were significantly associated with smaller hemispheric hippocampal volumes. IL measures were not significantly correlated with cerebral β-amyloid burden, though a trend was present and effect sizes were mild. These hippocampal volume results suggest that this IL task may be sensitive to AD pathology along the AD continuum. [ABSTRACT FROM AUTHOR]
Copyright of Developmental Neuropsychology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Examining the Relationship between a Verbal Incidental Learning Measure from the WAIS-IV and Neuroimaging Biomarkers for Alzheimer's Pathology.
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  Data: <searchLink fieldCode="JN" term="%22Developmental+Neuropsychology%22">Developmental Neuropsychology</searchLink>. Apr-Jun2020, Vol. 45 Issue 3, p95-109. 15p. 4 Charts, 2 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Incidental+learning%22">Incidental learning</searchLink><br /><searchLink fieldCode="DE" term="%22Verbal+learning%22">Verbal learning</searchLink><br /><searchLink fieldCode="DE" term="%22Neuropsychological+tests%22">Neuropsychological tests</searchLink><br /><searchLink fieldCode="DE" term="%22Wechsler+Adult+Intelligence+Scale%22">Wechsler Adult Intelligence Scale</searchLink><br /><searchLink fieldCode="DE" term="%22Pathology%22">Pathology</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+imaging%22">Brain imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Biomarkers%22">Biomarkers</searchLink>
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  Data: Convergent validation of a verbal incidental learning (IL) task from the WAIS-IV using neuroimaging biomarkers is warranted to understand its sensitivity to Alzheimer's disease (AD) pathology. Fifty-five memory clinic patients aged 59 to 87 years received neuropsychological assessment, and measures of IL and quantitative brain imaging. Worse IL-Total Score and IL-Similarities performances were significantly associated with smaller hemispheric hippocampal volumes. IL measures were not significantly correlated with cerebral β-amyloid burden, though a trend was present and effect sizes were mild. These hippocampal volume results suggest that this IL task may be sensitive to AD pathology along the AD continuum. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Developmental Neuropsychology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1080/87565641.2020.1762602
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        Text: English
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        Type: general
      – SubjectFull: Verbal learning
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      – SubjectFull: Neuropsychological tests
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      – SubjectFull: Wechsler Adult Intelligence Scale
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      – SubjectFull: Brain imaging
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              Text: Apr-Jun2020
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              Y: 2020
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