Neurophysiological challenges in myasthenia gravis associated with MuSK antibodies: a case report.
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| Title: | Neurophysiological challenges in myasthenia gravis associated with MuSK antibodies: a case report. |
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| Authors: | Monte, Gabriele (AUTHOR), Evoli, Amelia (AUTHOR), Sanders, Donald B. (AUTHOR), Modoni, Anna (AUTHOR) |
| Source: | Neurological Sciences. Jul2022, Vol. 43 Issue 7, p4591-4593. 3p. 2 Graphs. |
| Subjects: | Myasthenia gravis, Action potentials, Motor unit, Immunoglobulins |
| Abstract: | Repetitive nerve stimulation (RNS) in limb muscles has low sensitivity in myasthenia gravis with muscle-specific tyrosine kinase antibodies (MuSK-MG) given the predominant involvement of cranial and neck muscles [[1]]. MG was diagnosed after single-fiber EMG (SF-EMG) of the frontalis muscle showed increased jitter (no details available) and serum MuSK antibody (Ab) was detected by standard radioimmunoassay (RIA) (1.12 nMol/L, reference < 0.05). Needle electromyography (EMG) of the deltoid muscle showed polyphasic motor unit action potentials (MUAPs) of reduced amplitude associated with fibrillation potentials; 3 Hz RNS of the axillary nerve did not show a decremental pattern. [Extracted from the article] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Repetitive nerve stimulation (RNS) in limb muscles has low sensitivity in myasthenia gravis with muscle-specific tyrosine kinase antibodies (MuSK-MG) given the predominant involvement of cranial and neck muscles [[1]]. MG was diagnosed after single-fiber EMG (SF-EMG) of the frontalis muscle showed increased jitter (no details available) and serum MuSK antibody (Ab) was detected by standard radioimmunoassay (RIA) (1.12 nMol/L, reference < 0.05). Needle electromyography (EMG) of the deltoid muscle showed polyphasic motor unit action potentials (MUAPs) of reduced amplitude associated with fibrillation potentials; 3 Hz RNS of the axillary nerve did not show a decremental pattern. [Extracted from the article] |
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| ISSN: | 15901874 |
| DOI: | 10.1007/s10072-022-06013-y |
