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PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.

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Title: PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.
Authors: Fisch, Daniel, Pfleiderer, Moritz M., Anastasakou, Eleni, Mackie, Gillian M., Wendt, Fabian, Xiangyang Liu, Clough, Barbara, Lara-Reyna, Samuel, Encheva, Vesela, Snijders, Ambrosius P., Bando, Hironori, Yamamoto, Masahiro, Beggs, Andrew D., Mercer, Jason, Shenoy, Avinash R., Wollscheid, Bernd, Maslowski, Kendle M., Galej, Wojtek P., Frickel, Eva-Maria
Source: Science (pre-March 2025). 10/6/2023, Vol. 382 Issue 6666, p67-67. 1p. 1 Diagram.
Subjects: Apoptosis, Cell morphology
Abstract: The article focuses on how cells protect themselves from self-damage caused by interferon-stimulated genes (ISGs), specifically guanylate-binding proteins (GBPs), in response to interferon-g (IFN-g) stimulation, and how the kinase PIM1 controls GBP1 activity to prevent cellular damage while maintaining its antimicrobial function in human macrophages.
Database: Psychology and Behavioral Sciences Collection
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Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 172833624
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.
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  Data: <searchLink fieldCode="AR" term="%22Fisch%2C+Daniel%22">Fisch, Daniel</searchLink><br /><searchLink fieldCode="AR" term="%22Pfleiderer%2C+Moritz+M%2E%22">Pfleiderer, Moritz M.</searchLink><br /><searchLink fieldCode="AR" term="%22Anastasakou%2C+Eleni%22">Anastasakou, Eleni</searchLink><br /><searchLink fieldCode="AR" term="%22Mackie%2C+Gillian+M%2E%22">Mackie, Gillian M.</searchLink><br /><searchLink fieldCode="AR" term="%22Wendt%2C+Fabian%22">Wendt, Fabian</searchLink><br /><searchLink fieldCode="AR" term="%22Xiangyang+Liu%22">Xiangyang Liu</searchLink><br /><searchLink fieldCode="AR" term="%22Clough%2C+Barbara%22">Clough, Barbara</searchLink><br /><searchLink fieldCode="AR" term="%22Lara-Reyna%2C+Samuel%22">Lara-Reyna, Samuel</searchLink><br /><searchLink fieldCode="AR" term="%22Encheva%2C+Vesela%22">Encheva, Vesela</searchLink><br /><searchLink fieldCode="AR" term="%22Snijders%2C+Ambrosius+P%2E%22">Snijders, Ambrosius P.</searchLink><br /><searchLink fieldCode="AR" term="%22Bando%2C+Hironori%22">Bando, Hironori</searchLink><br /><searchLink fieldCode="AR" term="%22Yamamoto%2C+Masahiro%22">Yamamoto, Masahiro</searchLink><br /><searchLink fieldCode="AR" term="%22Beggs%2C+Andrew+D%2E%22">Beggs, Andrew D.</searchLink><br /><searchLink fieldCode="AR" term="%22Mercer%2C+Jason%22">Mercer, Jason</searchLink><br /><searchLink fieldCode="AR" term="%22Shenoy%2C+Avinash+R%2E%22">Shenoy, Avinash R.</searchLink><br /><searchLink fieldCode="AR" term="%22Wollscheid%2C+Bernd%22">Wollscheid, Bernd</searchLink><br /><searchLink fieldCode="AR" term="%22Maslowski%2C+Kendle+M%2E%22">Maslowski, Kendle M.</searchLink><br /><searchLink fieldCode="AR" term="%22Galej%2C+Wojtek+P%2E%22">Galej, Wojtek P.</searchLink><br /><searchLink fieldCode="AR" term="%22Frickel%2C+Eva-Maria%22">Frickel, Eva-Maria</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Science+%28pre-March+2025%29%22">Science (pre-March 2025)</searchLink>. 10/6/2023, Vol. 382 Issue 6666, p67-67. 1p. 1 Diagram.
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  Data: <searchLink fieldCode="DE" term="%22Apoptosis%22">Apoptosis</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+morphology%22">Cell morphology</searchLink>
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  Data: The article focuses on how cells protect themselves from self-damage caused by interferon-stimulated genes (ISGs), specifically guanylate-binding proteins (GBPs), in response to interferon-g (IFN-g) stimulation, and how the kinase PIM1 controls GBP1 activity to prevent cellular damage while maintaining its antimicrobial function in human macrophages.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=172833624
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        Text: English
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              Text: 10/6/2023
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              Y: 2023
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