Acceptability of antipsychotic transdermal patch for acute schizophrenia: a systematic review and meta‐analysis.
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| Title: | Acceptability of antipsychotic transdermal patch for acute schizophrenia: a systematic review and meta‐analysis. |
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| Authors: | Kishi, Taro (AUTHOR), Citrome, Leslie (AUTHOR), Sakuma, Kenji (AUTHOR), Hamanaka, Shun (AUTHOR), Nishii, Yasufumi (AUTHOR), Iwata, Nakao (AUTHOR) |
| Source: | Psychiatry & Clinical Neurosciences. Apr2024, Vol. 78 Issue 4, p260-262. 3p. |
| Subjects: | Transdermal medication, Drug formularies, Schizophrenia, Publication bias, Medical education, Grants in aid (Public finance), Medical research |
| Abstract: | This article discusses the acceptability of antipsychotic transdermal patches as a treatment option for acute schizophrenia. Antipsychotic medications are commonly used for managing psychosis and preventing relapse in individuals with schizophrenia. While previous studies have shown that long-acting injectable antipsychotics are more effective in preventing relapse compared to oral antipsychotics, the role of transdermal delivery systems remains unclear. The authors conducted a systematic review and meta-analysis comparing the acceptability of transdermal patches versus oral antipsychotics in people with acute schizophrenia. The results suggest that transdermal patches may be more acceptable in terms of all-cause discontinuation rates, potentially due to their favorable tolerability profile and visible proof of adherence. However, further research is needed to fully understand the acceptability and treatment outcomes of different formulations. [Extracted from the article] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | This article discusses the acceptability of antipsychotic transdermal patches as a treatment option for acute schizophrenia. Antipsychotic medications are commonly used for managing psychosis and preventing relapse in individuals with schizophrenia. While previous studies have shown that long-acting injectable antipsychotics are more effective in preventing relapse compared to oral antipsychotics, the role of transdermal delivery systems remains unclear. The authors conducted a systematic review and meta-analysis comparing the acceptability of transdermal patches versus oral antipsychotics in people with acute schizophrenia. The results suggest that transdermal patches may be more acceptable in terms of all-cause discontinuation rates, potentially due to their favorable tolerability profile and visible proof of adherence. However, further research is needed to fully understand the acceptability and treatment outcomes of different formulations. [Extracted from the article] |
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| ISSN: | 13231316 |
| DOI: | 10.1111/pcn.13635 |
